慢性难愈性腿部溃疡治疗的一种新方法。

A new approach in the management of chronic nonhealing leg ulcers.

作者信息

Saber Alan A, Yahya Kareem Z, Rao Arun, Castellano Michael, Cioroiu Michael, Grossi Robert, Tornambe Robert M

机构信息

Department of Surgery, Michigan State University, Kalamazoo Center for Medical Studies, Kalamazoo, Michigan 49008, USA.

出版信息

J Invest Surg. 2005 Nov-Dec;18(6):321-3. doi: 10.1080/08941930500328821.

DOI:10.1080/08941930500328821

PMID:16319053

Abstract

Chronic leg ulcers are a major cause of mortality and morbidity. The efficacy of hyperbaric oxygen treatment is being evaluated in the management of nonhealing leg ulcers to improve skin graft survival. Twenty-seven patients with 36 chronic leg ulcers were examined. Each wound received 12 preoperative hyperbaric oxygen treatments, split-thickness skin grafting, followed by 12 postoperative hyperbaric oxygen treatments. Wound transcutaneous oxygen tension measurements (TCOM) were taken. The graft take was evaluated. At 18 months follow-up, 18 skin grafts (50%) showed complete take, 15 (41.7%) demonstrated partial take, and 3 (8.3%) failed. Hyperbaric oxygen treatment is an effective adjunct in the management of chronic leg ulcers, and its use resulted in increased graft take and survival.

摘要

慢性腿部溃疡是导致死亡和发病的主要原因。正在评估高压氧治疗在不愈合腿部溃疡管理中的疗效，以提高皮肤移植的存活率。对27例患有36处慢性腿部溃疡的患者进行了检查。每个伤口术前接受12次高压氧治疗，然后进行分层皮片移植，术后再接受12次高压氧治疗。进行伤口经皮氧分压测量（TCOM）。评估移植皮片的存活情况。在18个月的随访中，18块皮肤移植片（50%）完全存活，15块（41.7%）部分存活，3块（8.3%）失败。高压氧治疗是慢性腿部溃疡管理中的一种有效辅助手段，其应用提高了移植皮片的存活和成活率。