Agich G J, Siemionow M
Department of Bioethics, Transplant Center, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
J Med Ethics. 2005 Dec;31(12):707-9. doi: 10.1136/jme.2005.011841.
The ethical discussion of facial allograft transplantation (FAT) for severe facial deformity, popularly known as facial transplantation, has been one sided and sensationalistic. It is based on film and fiction rather than science and clinical experience. Based on our experience in developing the first IRB approved protocol for FAT, we critically discuss the problems with this discussion, which overlooks the plight of individuals with severe facial deformities. We discuss why FAT for facial deformity is ethically and surgically justified despite its negative portrayal in the media.
针对严重面部畸形进行面部同种异体移植（FAT）（通常称为面部移植）的伦理讨论一直是片面且耸人听闻的。它基于电影和虚构内容，而非科学和临床经验。基于我们在制定首个经机构审查委员会（IRB）批准的FAT方案过程中的经验，我们批判性地讨论了这种讨论中存在的问题，该讨论忽视了严重面部畸形患者的困境。我们讨论了尽管面部畸形的FAT在媒体上有负面描述，但在伦理和外科手术方面仍具有合理性的原因。
