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CT灌注成像在急性卒中早期诊断中的应用

CT perfusion imaging in the early diagnosis of acute stroke.

作者信息

Tekşam Mehmet, Cakir Banu, Coşkun Mehmet

机构信息

Department of Radiology, Başkent University School of Medicine, Ankara, Turkey, Turkey.

出版信息

Diagn Interv Radiol. 2005 Dec;11(4):202-5.

PMID:16320225
Abstract

Early diagnosis of acute cerebral infarction is critical due to the time limit of thrombolytic treatment. Cerebral computed tomography (CT) perfusion imaging is a new technique, which appears to provide early diagnosis of major vessel occlusions in the brain. CT perfusion imaging also provides valuable information about the hemodynamic status of ischemic brain tissue. In this report, we present the CT perfusion findings in comparison to the non-contrast CT and diffusion-weighted (DW) magnetic resonance (MR) imaging findings in two cases of acute cerebral infarction. Non-contrast CT findings were non-specific in the first case and there was minimal hypoattenuation in the superior aspect of the lentiform nucleus in the second case. CT perfusion imaging demonstrated significant perfusion defects in the middle cerebral artery territory in both cases. DW-MR imaging confirmed acute infarctions, which were smaller than the perfusion defect areas in the CT perfusion imaging in both cases.

摘要

由于溶栓治疗存在时间限制,急性脑梗死的早期诊断至关重要。脑计算机断层扫描(CT)灌注成像是一项新技术,似乎能够对大脑主要血管闭塞进行早期诊断。CT灌注成像还能提供有关缺血性脑组织血流动力学状态的有价值信息。在本报告中,我们展示了两例急性脑梗死患者的CT灌注成像结果,并与非增强CT及扩散加权(DW)磁共振(MR)成像结果进行了比较。第一例患者的非增强CT表现不具有特异性,第二例患者的豆状核上部有轻微低密度影。两例患者的CT灌注成像均显示大脑中动脉供血区存在明显灌注缺损。DW-MR成像证实了急性梗死灶,两例患者的梗死灶均小于CT灌注成像中的灌注缺损区域。

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Indian J Radiol Imaging. 2008 Nov;18(4):281-6. doi: 10.4103/0971-3026.43837.
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Hyperacute stroke patients and catheter thrombolysis therapy: correlation between computed tomography perfusion maps and final infarction.
超急性卒中患者与导管溶栓治疗:计算机断层扫描灌注图与最终梗死之间的相关性
Radiat Med. 2008 May;26(4):227-36. doi: 10.1007/s11604-007-0219-2. Epub 2008 May 29.