Izmaĭlov S G, Beschastnov V V, Garaev V N, Artifeksova A A, Bodrov A A, Botiakov A A, Izmaĭlov A G
Vestn Ross Akad Med Nauk. 2005(10):25-30.
The authors performed an animal model study of postoperative wound complications using 72 white Wistar rats and 36 mongrel dogs with aseptic cut wounds, granulating wounds, and relaparotomic wounds. In the control group the wounds were closed by a conventional method; in the main group a machine stitch was performed. Wound closure in the main group was performed after approximation of wound edges with specially constructed devices. Morphological and microbiological analysis showed that the key role in development of complications is played by morphofunctional wound substrate, which comprises the degree of paravulnar tissue traumatization with suture when a conventional method is used, and paravulnar tissue ischemia in case of microbial dissemination. The authors conclude that machine stitch is preferable.
作者使用72只白色Wistar大鼠和36只杂种犬，制作了无菌切割伤口、肉芽创面和再次剖腹伤口的术后伤口并发症动物模型研究。对照组伤口采用传统方法缝合；主要组采用机器缝合。主要组在使用特制装置使伤口边缘对合后进行伤口缝合。形态学和微生物学分析表明，并发症发生的关键作用由形态功能伤口基质发挥，当使用传统方法时，其包括缝合时尺侧旁组织的创伤程度，以及在微生物传播情况下的尺侧旁组织缺血。作者得出结论，机器缝合更可取。
