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晚期多发性硬化症的膀胱保守管理

Conservative bladder management in advanced multiple sclerosis.

作者信息

De Ridder D, Ost D, Van der Aa F, Stagnaro M, Beneton C, Gross-Paju K, Eelen P, Limbourg H, Harper M, Segal J C, Fowler C J, Nordenbo A

机构信息

Department of Urology, University Hospitals KU Leuven, Belgium.

出版信息

Mult Scler. 2005 Dec;11(6):694-9. doi: 10.1191/1352458505ms1237oa.

DOI:10.1191/1352458505ms1237oa
PMID:16320730
Abstract

Anticholinergics and intermittent catheterization are the cornerstones of bladder management in early multiple sclerosis (MS). In advanced MS however, bladder management is based more on tradition than on evidence. Nurses seem to deal with catheter problems and chronic incontinence. Despite the abundant use of indwelling catheters, there is a lack for guidelines on catheter-induced problems. The psychosexual and social impact of bladder problems in advanced MS is often neglected. The international multidisciplinary special interest group on sexual, urological and bowel dysfunction in MS (SUBDIMS) as a special interest group of the Rehabilitation in Multiple Sclerosis (RIMS) was confronted with a high variability in practice and a lack of guidelines. A literature review was prepared during three multidisciplinary expert meetings. This review will be the basis of further initiatives to improve the urological treatment of patients with advanced MS.

摘要

抗胆碱能药物和间歇性导尿是早期多发性硬化症(MS)膀胱管理的基石。然而,在晚期MS中,膀胱管理更多地基于传统而非证据。护士似乎在处理导尿管问题和慢性尿失禁。尽管留置导尿管使用广泛,但缺乏关于导尿管引发问题的指南。晚期MS中膀胱问题对心理性和社会性的影响常常被忽视。作为多发性硬化症康复(RIMS)特别兴趣小组的国际多学科性、泌尿和肠道功能障碍特别兴趣小组(SUBDIMS)面临着实践中的高度变异性和缺乏指南的问题。在三次多学科专家会议期间进行了文献综述。这篇综述将作为进一步改善晚期MS患者泌尿外科治疗举措的基础。

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引用本文的文献

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European Academy of Neurology (EAN)/European Federation of Autonomic Societies (EFAS)/International Neuro-Urology Society (INUS) Guidelines for Practising Neurologists on the Assessment and Treatment of Neurogenic Urinary and Sexual Symptoms (NEUROGED Guidelines).欧洲神经病学学会(EAN)/欧洲自主神经学会联合会(EFAS)/国际神经泌尿学会(INUS)针对神经科医生的神经源性泌尿和性症状评估与治疗指南(NEUROGED指南)
Eur J Neurol. 2025 Apr;32(4):e70119. doi: 10.1111/ene.70119.
2
Lower urinary tract disorders in multiple sclerosis patients: prevalence, clinical features, and response to treatments.多发性硬化症患者的下尿路障碍:患病率、临床特征和治疗反应。
Neurourol Urodyn. 2021 Aug;40(6):1500-1508. doi: 10.1002/nau.24687. Epub 2021 Jun 3.
3
Management of neurogenic bladder in patients with multiple sclerosis.多发性硬化症患者的神经源性膀胱管理。
Nat Rev Urol. 2016 May;13(5):275-88. doi: 10.1038/nrurol.2016.53. Epub 2016 Mar 31.
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TRP channels in lower urinary tract dysfunction.下尿路功能障碍中的瞬时受体电位通道
Br J Pharmacol. 2014 May;171(10):2537-51. doi: 10.1111/bph.12502.
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Caregiver burden among informal caregivers assisting people with multiple sclerosis.协助多发性硬化症患者的非正式照料者的照料负担
Int J MS Care. 2011 Summer;13(2):76-83. doi: 10.7224/1537-2073-13.2.76.
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Pannexin 1 involvement in bladder dysfunction in a multiple sclerosis model.缝隙连接蛋白 1 参与多发性硬化症模型中的膀胱功能障碍。
Sci Rep. 2013;3:2152. doi: 10.1038/srep02152.
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Impact of intermittent catheterization on the quality of life of multiple sclerosis patients.间歇性导尿对多发性硬化症患者生活质量的影响。
World J Urol. 2013 Dec;31(6):1445-50. doi: 10.1007/s00345-012-1017-8. Epub 2013 Jan 6.
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Sacral neuromodulation in patients with multiple sclerosis.骶神经调节在多发性硬化症患者中的应用。
World J Urol. 2012 Feb;30(1):123-8. doi: 10.1007/s00345-011-0669-0. Epub 2011 Mar 15.
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The symptomatic management of multiple sclerosis.多发性硬化症的症状管理。
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