Kolesnikova I Iu, Beliaeva G S, Leont'eva V A
Klin Med (Mosk). 2005;83(10):33-6.
The article is dedicated to changes in life quality (LQ) and mental status, and to forming of various types of response to the disease in patients with benign and unfavorable course of peptic ulcer (PU). The subjects were 140 patients in acute phase of PU, in 66 of whom the course of the disease was benign, and in 74--unfavorable. In both groups there were patients with low and satisfactory LQ. High level of nervousness was typical of patients with low LQ and benign course of the disease. Patients with satisfactory LQ and unfavorable course of the disease were characterized by minor personality changes, but developed an agnostic response to the disease much more frequently. Reduction of compliance was found mainly in patients with low LQ and an agnostic response; this should be taken into consideration while correcting the therapy.
本文致力于探讨消化性溃疡（PU）病情呈良性和不良转归的患者的生活质量（LQ）变化、精神状态以及对疾病形成的各种反应类型。研究对象为140例处于PU急性期的患者，其中66例病情呈良性，74例病情不良。两组患者中均有LQ较低和LQ令人满意的情况。LQ较低且病情呈良性的患者具有高度紧张的特点。LQ令人满意但病情不良的患者表现为轻微的人格变化，但对疾病产生不可知反应的频率更高。依从性降低主要见于LQ较低且有不可知反应的患者；在调整治疗方案时应考虑到这一点。
