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棘阿米巴角膜炎的海德堡视网膜断层扫描仪II检查结果

Heidelberg retina tomograph II findings of Acanthamoeba keratitis.

作者信息

Bourcier Tristan, Dupas Bénédicte, Borderie Vincent, Chaumeil Christine, Larricart Pierre, Baudouin Christophe, Laroche Laurent

机构信息

Quinze-Vingts National Center of Ophthalmology, Universities Paris 6 and Paris 5, Paris, France.

出版信息

Ocul Immunol Inflamm. 2005 Dec;13(6):487-92. doi: 10.1080/09273940590951098.

Abstract

PURPOSE

Heidelberg retina tomograph II (HRTII) examination was performed with cornea module in one patient with Acanthamoeba keratitis (AK) to provide images detailing characteristic findings of the disease.

METHODS

A 34-year-old woman presented with clinical signs and symptoms of AK. HRTII with cornea module was performed and the patient underwent laboratory investigations.

RESULTS

HRTII examination with cornea module revealed numerous 20-26-micro m diameter high-contrast round particles within the corneal epithelium and anterior stroma, resembling Acanthamoeba cysts. Stellate cells as well as ovoid irregular objects, possibly inflammatory cells, trophozoites, altered cysts, or activated keratocytes, were also present in the area of stromal infiltrates. Laboratory investigations confirmed the diagnosis of AK.

CONCLUSIONS

HRTII cornea module can be helpful in the diagnosis of AK by identifying acanthamoeba cyst-like structures in the cornea. This technique also has potential uses in monitoring the efficiency of anti-infective treatment.

摘要

目的

对1例棘阿米巴角膜炎(AK)患者使用角膜模块进行海德堡视网膜断层扫描仪II(HRTII)检查,以提供详细显示该病特征性表现的图像。

方法

一名34岁女性出现AK的临床症状和体征。进行了带角膜模块的HRTII检查,并对该患者进行了实验室检查。

结果

带角膜模块的HRTII检查显示,角膜上皮和前基质内有大量直径20 - 26微米的高对比度圆形颗粒,类似棘阿米巴囊肿。在基质浸润区域还存在星状细胞以及卵圆形不规则物体,可能为炎性细胞、滋养体、变形囊肿或活化的角膜细胞。实验室检查确诊为AK。

结论

HRTII角膜模块通过识别角膜中棘阿米巴囊肿样结构,有助于AK的诊断。该技术在监测抗感染治疗效果方面也有潜在用途。

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