志贺毒素1转化噬菌体BP-4795编码一种NleA样III型效应蛋白。
The Shiga toxin 1-converting bacteriophage BP-4795 encodes an NleA-like type III effector protein.
作者信息
Creuzburg Kristina, Recktenwald Jürgen, Kuhle Volker, Herold Sylvia, Hensel Michael, Schmidt Herbert
机构信息
Institute of Medical Microbiology and Hygiene, Technical University of Dresden, 01307 Dresden, Germany.
出版信息
J Bacteriol. 2005 Dec;187(24):8494-8. doi: 10.1128/JB.187.24.8494-8498.2005.
Abstract
In this study, the complete DNA sequence of Shiga toxin 1-converting bacteriophage BP-4795 was determined. The genome of BP-4795 consists of 85 open reading frames, including two complete IS629 elements and three morons at the end of its late regulatory region. One of these morons encodes a type III effector that is translocated by the locus of enterocyte effacement-encoded type III secretion system into HeLa cells, where it localizes with the Golgi apparatus.
摘要
在本研究中，测定了志贺毒素1转换噬菌体BP - 4795的完整DNA序列。BP - 4795的基因组由85个开放阅读框组成，包括两个完整的IS629元件以及其晚期调控区域末端的三个moron。这些moron之一编码一种III型效应蛋白，该蛋白通过肠细胞脱落编码的III型分泌系统转运至HeLa细胞，并定位于高尔基体。
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3
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J Med Microbiol. 2004 Nov;53(Pt 11):1145-1149. doi: 10.1099/jmm.0.45684-0.
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