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CDK2 inhibition disorders centrosome stoichiometry and alters cellular outcomes in aneuploid cancer cells.
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Chlamydia and HPV induce centrosome amplification in the host cell through additive mechanisms.
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Human papillomavirus E6 and E7: What remains?
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SKA3 Promotes tumor growth by regulating CDK2/P53 phosphorylation in hepatocellular carcinoma.
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The SKP1-Cullin-F-box E3 ligase βTrCP and CDK2 cooperate to control STIL abundance and centriole number.
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A tentative classification of centrosome abnormalities in cancer.
Cell Biol Int. 2005 May;29(5):352-9. doi: 10.1016/j.cellbi.2005.03.005.
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The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles.
Mol Biol Cell. 2005 Mar;16(3):1095-107. doi: 10.1091/mbc.e04-10-0939. Epub 2004 Dec 22.
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A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry.
Science. 2004 Oct 29;306(5697):885-8. doi: 10.1126/science.1103544.
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Molecular signature of oncogenic ras-induced senescence.
Oncogene. 2004 Dec 9;23(57):9238-46. doi: 10.1038/sj.onc.1208172.
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Cyclin-dependent kinase inhibitor indirubin-3'-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies.
Oncogene. 2004 Oct 28;23(50):8206-15. doi: 10.1038/sj.onc.1208012.
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The arithmetic of centrosome biogenesis.
J Cell Sci. 2004 Apr 1;117(Pt 9):1619-30. doi: 10.1242/jcs.01128.
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Cdk2 knockout mice are viable.
Curr Biol. 2003 Oct 14;13(20):1775-85. doi: 10.1016/j.cub.2003.09.024.
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Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.
Nat Genet. 2003 Sep;35(1):25-31. doi: 10.1038/ng1232. Epub 2003 Aug 17.
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Centrosome number is controlled by a centrosome-intrinsic block to reduplication.
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Proliferation of cancer cells despite CDK2 inhibition.
Cancer Cell. 2003 Mar;3(3):233-45. doi: 10.1016/s1535-6108(03)00053-9.
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