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Sildenafil--a possible treatment for acute pulmonary hypertension during cardiac surgery.

作者信息

Wheeler Wendy, Hayes Shelly, Nguyen Ngo, Cilla Anthony M, Rybowicz Joseph, Jones Comeco C, Ramsay Michael A E, Hall Shelley A, Meyer Dan, Capehart John, Jessen Michael E, Ring Steves

机构信息

Department of Anesthesia and Pain Management, Baylor University Medical Center, Dallas, Texas 75246, USA.

出版信息

Proc (Bayl Univ Med Cent). 2002 Jan;15(1):13-5. doi: 10.1080/08998280.2002.11927806.

DOI:10.1080/08998280.2002.11927806
PMID:16333399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1276328/
Abstract
摘要

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1
Sildenafil--a possible treatment for acute pulmonary hypertension during cardiac surgery.西地那非——心脏手术期间急性肺动脉高压的一种可能治疗方法。
Proc (Bayl Univ Med Cent). 2002 Jan;15(1):13-5. doi: 10.1080/08998280.2002.11927806.
2
Inhaled NO and sildenafil combination in cardiac surgery patients with out-of-proportion pulmonary hypertension: acute effects on postoperative gas exchange and hemodynamics.吸入一氧化氮和西地那非联合治疗肺血管阻力比例失调的心脏手术患者：对术后气体交换和血液动力学的急性影响。
Circ Heart Fail. 2012 Jan;5(1):47-53. doi: 10.1161/CIRCHEARTFAILURE.111.963314. Epub 2011 Nov 4.
3
Effects of escalating doses of sildenafil on hemodynamics and gas exchange in children with pulmonary hypertension and congenital cardiac defects.递增剂量西地那非对患有肺动脉高压和先天性心脏缺陷儿童的血流动力学和气体交换的影响。
J Cardiothorac Vasc Anesth. 2007 Apr;21(2):203-7. doi: 10.1053/j.jvca.2006.02.010. Epub 2006 May 18.
4
[Sildenafil for pulmonary hypertension treatment after cardiac surgery].[西地那非用于心脏手术后肺动脉高压的治疗]
J Pediatr (Rio J). 2005 Mar-Apr;81(2):175-8.
5
Sildenafil for primary and secondary pulmonary hypertension.西地那非用于原发性和继发性肺动脉高压。
Clin Pharmacol Ther. 2002 May;71(5):398-402. doi: 10.1067/mcp.2002.123554.
6
[Treatment with oral sildenafil in patients with severe pulmonary hypertension after open heart operations].[口服西地那非治疗心脏直视手术后重症肺动脉高压患者]
Zhonghua Xin Xue Guan Bing Za Zhi. 2005 Oct;33(10):916-9.
7
Oral sildenafil reduces pulmonary hypertension after cardiac surgery.口服西地那非可降低心脏手术后的肺动脉高压。
Ann Thorac Surg. 2005 Jan;79(1):194-7; discussion 194-7. doi: 10.1016/j.athoracsur.2004.06.086.
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Effect of oral sildenafil citrate on intraoperative hemodynamics in patients with pulmonary hypertension undergoing valvular heart surgery.口服枸橼酸西地那非对接受心脏瓣膜手术的肺动脉高压患者术中血流动力学的影响。
J Thorac Cardiovasc Surg. 2006 Dec;132(6):1420-5. doi: 10.1016/j.jtcvs.2006.08.035.
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Comparison of the therapeutic effects and side effects of tadalafil and sildenafil after surgery in young infants with pulmonary arterial hypertension due to systemic-to-pulmonary shunts.体肺分流所致肺动脉高压婴幼儿术后他达拉非与西地那非治疗效果及副作用的比较
Cardiol Young. 2017 Nov;27(9):1686-1693. doi: 10.1017/S1047951117000981.
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Use of sildenafil to facilitate weaning from inhaled nitric oxide in children with pulmonary hypertension following surgery for congenital heart disease.使用西地那非促进先天性心脏病手术后肺动脉高压患儿撤离吸入一氧化氮。
J Intensive Care Med. 2008 Sep-Oct;23(5):329-34. doi: 10.1177/0885066608321389. Epub 2008 Aug 12.

本文引用的文献

1
Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension.吸入伊洛前列素联合口服西地那非对原发性肺动脉高压患者的疗效
Circulation. 2001 Sep 11;104(11):1218-22. doi: 10.1161/hc3601.096826.
2
Sildenafil inhibits hypoxia-induced pulmonary hypertension.西地那非可抑制缺氧诱导的肺动脉高压。
Circulation. 2001 Jul 24;104(4):424-8. doi: 10.1161/hc2901.093117.
3
Therapy of pulmonary hypertension: targeting pathogenic mechanisms with selective treatment delivery.肺动脉高压的治疗：通过选择性治疗递送靶向致病机制。
Crit Care Med. 2001 May;29(5):1086-7. doi: 10.1097/00003246-200105000-00047.
4
Nebulized sildenafil is a selective pulmonary vasodilator in lambs with acute pulmonary hypertension.雾化吸入西地那非对患有急性肺动脉高压的羔羊是一种选择性肺血管扩张剂。
Crit Care Med. 2001 May;29(5):1000-5. doi: 10.1097/00003246-200105000-00024.
5
Sildenafil (viagra) facilitates weaning of inhaled nitric oxide following placement of a biventricular-assist device.西地那非（伟哥）有助于在植入双心室辅助装置后停用吸入一氧化氮。
J Clin Anesth. 2001 May;13(3):218-20. doi: 10.1016/s0952-8180(01)00252-5.
6
Sildenafil in primary pulmonary hypertension.西地那非治疗原发性肺动脉高压
N Engl J Med. 2000 Nov 2;343(18):1342. doi: 10.1056/NEJM200011023431814.
7
Viagra for impotence of pulmonary vasodilator therapy?伟哥用于治疗肺血管扩张剂治疗无效的阳痿？
Am J Respir Crit Care Med. 2001 Feb;163(2):312-3. doi: 10.1164/ajrccm.163.2.ed2000e.
8
Inhaled nitric oxide reduces the need for extracorporeal membrane oxygenation in infants with persistent pulmonary hypertension of the newborn.吸入一氧化氮可减少新生儿持续性肺动脉高压患儿对体外膜肺氧合的需求。
Crit Care Med. 2000 Nov;28(11):3722-7. doi: 10.1097/00003246-200011000-00031.
9
Combined therapy with zaprinast and inhaled nitric oxide abolishes hypoxic pulmonary hypertension.
Crit Care Med. 2000 Jul;28(7):2420-4. doi: 10.1097/00003246-200007000-00038.
10
Sildenafil as a selective pulmonary vasodilator in childhood primary pulmonary hypertension.西地那非作为儿童原发性肺动脉高压的一种选择性肺血管扩张剂。
Heart. 2000 Aug;84(2):E4. doi: 10.1136/heart.84.2.e4.