Evaluation of the efficacy of dill apiol and pyriproxyfen in the treatment and control of Xenopsylla cheopis flea Roths (Siphonaptera: Pulicidae).

The effect of LC50 of the isolated dill apiol compound and pyriproxyfen caused significant prolongation in the first gonotrophic cycle and great reduction in the percentage of female (Xenopsylla cheopis) reproductive potential as well as egg hatchability. The results indicated that, the larval treatments inhibited the ovarian development and evolved drastic changes in the ovarian histology and histochemistry. The two tested compounds reduced the vitellogenesis and synthesis of carbohydrates, protein, DNA & RNA materials and lipids in oocytes. The two compounds are similar in their mode and site of action.