He Zhan-Ju, Jin Jie, Zhang Kai
Department of Urology, Peking University, Institute of Urology, First Hospital, Beijing 100034, China.
Zhonghua Nan Ke Xue. 2005 Nov;11(11):841-2, 846.
To evaluate the efficacy and safety of sildenafil on erectile dysfunction in the aged men with diabetes.
One hundred and ten patients aged 55 years old above with type I or II diabetes and a minimum 3-month history of ED were studied. Patients were instructed to take one dose of their treatment orally at any time before anticipated sexual activity. Changes from baseline in mean scores on the erectile function domain of the International index of Erectile Function and changes from baseline in the proportion of "yes" responses to question 2, and 3, of the Sexual Encounter Profile were coprimary outcome measures.
Treatment with sildenafil significantly improved all primary efficacy variables.
Sildenafil therapy significantly enhanced erectile function and was well tolerated by men with diabetes and ED.
评估西地那非对老年糖尿病男性勃起功能障碍的疗效和安全性。
研究了110例年龄在55岁及以上的I型或II型糖尿病患者，他们患有勃起功能障碍至少3个月。患者被指示在预期性活动前的任何时间口服一剂治疗药物。国际勃起功能指数勃起功能领域的平均得分相对于基线的变化，以及性接触概况中问题2和3的“是”回答比例相对于基线的变化是共同主要结局指标。
西地那非治疗显著改善了所有主要疗效变量。
西地那非治疗显著增强了勃起功能，并且糖尿病和勃起功能障碍男性对其耐受性良好。
