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Tyrosine kinases and their interactions with signalling proteins.

作者信息

Pawson T

机构信息

Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

出版信息

Curr Opin Genet Dev. 1992 Feb;2(1):4-12. doi: 10.1016/s0959-437x(05)80314-4.

DOI:10.1016/s0959-437x(05)80314-4
PMID:1633425
Abstract

Recent progress has been made in identifying signal transduction pathways controlled by receptor protein-tyrosine kinases. The receptors for nerve growth factor and hepatocyte growth factor have been identified as the Trk and Met tyrosine kinases. The stimulation of intracellular signal transduction pathways by activated receptors appears to involve the association of SH2-containing cytoplasmic signalling proteins with autophosphorylated receptors.

摘要

相似文献

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Tyrosine kinases and their interactions with signalling proteins.
Curr Opin Genet Dev. 1992 Feb;2(1):4-12. doi: 10.1016/s0959-437x(05)80314-4.
2
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Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells.在人类嗜T淋巴细胞病毒I型（HTLV-I）感染的人T细胞中，LCK激酶和FYN激酶对于白细胞介素-2（IL-2）介导的信号转导都不是必需的。
Int Immunol. 1992 Nov;4(11):1233-43. doi: 10.1093/intimm/4.11.1233.

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