流感病毒的基因分析
Genetic analysis of influenza virus.
作者信息
Luo G, Palese P
机构信息
Department of Microbiology, Mount Sinai School of Medicine, New York, New York 10029-6574.
出版信息
Curr Opin Genet Dev. 1992 Feb;2(1):77-81. doi: 10.1016/s0959-437x(05)80326-0.
PMID:1633429
Abstract
The newly developed ribonucleoprotein reconstitution and transfection systems have facilitated the characterization of cis and trans functions required for transcription and replication of the influenza virus genome. For the first time, the genome of a negative-strand RNA virus can be manipulated using recombinant DNA techniques.
摘要
新开发的核糖核蛋白重组和转染系统有助于对流感病毒基因组转录和复制所需的顺式和反式功能进行表征。首次可以使用重组DNA技术来操纵负链RNA病毒的基因组。
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