Levy R M, Berger J R
Department of Neurosurgery, Northwestern University Medical School, Chicago, Illinois.
Neurosurg Clin N Am. 1992 Apr;3(2):443-70.
The spectrum of neurologic disease that complicates human immunodeficiency virus (HIV) is extremely broad. This article deals with those HIV-related diseases that may occur with a frequency of more than 1% and are of potential neurosurgical importance: those that result from a direct involvement of the nervous system by HIV and those that result either directly or indirectly from the concomitant immunosuppression. Infectious complications are the most common but not the sole cause of neurologic disability in the latter category. Other causes of neurologic disease seen in association with HIV infection include neoplasms, metabolic-nutritional disorders, and vascular complications.
使人类免疫缺陷病毒(HIV)病情复杂化的神经系统疾病谱极为广泛。本文论述那些发生率可能超过1%且具有潜在神经外科重要性的与HIV相关的疾病:即那些由HIV直接侵犯神经系统所致的疾病,以及那些直接或间接由伴随的免疫抑制所导致的疾病。感染性并发症是后一类中神经功能障碍最常见但并非唯一的病因。与HIV感染相关的其他神经系统疾病病因包括肿瘤、代谢营养障碍和血管并发症。