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中国患者的银屑病残疾指数:临床和心理变量的作用

The psoriasis disability index in Chinese patients: contribution of clinical and psychological variables.

作者信息

Yang Yong, Koh David, Khoo Lawrence, Nyunt Shwe Zin, Ng Vivian, Goh Chee Leok

机构信息

Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore, and the National Skin Center, Singapore.

出版信息

Int J Dermatol. 2005 Nov;44(11):925-9. doi: 10.1111/j.1365-4632.2004.02237.x.

Abstract

OBJECTIVES

To provide a description of medical and psychological aspects of Chinese psoriasis patients, and to examine the specific contribution of demographic, medical and psychological variables to the Psoriasis Disability Index.

METHODS

Ninety-three Chinese psoriasis patients underwent a clinical assessment using the Psoriasis Area and Severity Index (PASI) and completed a questionnaire that included questions on demographic and medical data, the Hospital Anxiety and Depression Scale (HADS) and the Psoriasis Disability Index (PDI).

RESULTS

Psoriasis patients with cosmetic involvement had higher levels of anxiety and depression and higher disability scores than those without cosmetic involvement. Thirty-four per cent of the patients reported a significant level of anxiety (HADS-anx. > 11). The clinical severity of psoriasis was not associated with psychological and PDI scores. Multiple regression analysis indicated that psychological variables were associated with PDI scores, and explained 30% of the variance. However, demographic and psoriasis severity variables explained only 6% of the variance.

CONCLUSION

Psoriasis patients suffer from anxiety and depression. Psychological factors are much stronger determinants of the PDI than demographic, disease related variables. Clinical management of the disease should consider both clinical and psychological factors.

摘要

目的

描述中国银屑病患者的医学和心理方面,并探讨人口统计学、医学和心理变量对银屑病残疾指数的具体影响。

方法

93名中国银屑病患者接受了使用银屑病面积和严重程度指数(PASI)的临床评估,并完成了一份问卷,其中包括有关人口统计学和医学数据、医院焦虑抑郁量表(HADS)和银屑病残疾指数(PDI)的问题。

结果

有外观受累的银屑病患者比无外观受累的患者焦虑和抑郁水平更高,残疾评分也更高。34%的患者报告有显著的焦虑水平(HADS-焦虑>11)。银屑病的临床严重程度与心理和PDI评分无关。多元回归分析表明,心理变量与PDI评分相关,并解释了30%的方差。然而,人口统计学和银屑病严重程度变量仅解释了6%的方差。

结论

银屑病患者存在焦虑和抑郁。心理因素比人口统计学、疾病相关变量更能决定PDI。该疾病的临床管理应同时考虑临床和心理因素。

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