Sampogna F, Tabolli S, Söderfeldt B, Axtelius B, Aparo U, Abeni D
Istituto Dermopatico dell'Immacolata IDI-IRCCS, Rome, Italy.
Br J Dermatol. 2006 May;154(5):844-9. doi: 10.1111/j.1365-2133.2005.07071.x.
Different specific and generic instruments are used to evaluate quality of life in dermatology, but their interrelationship is not well known.
To describe the quality of life in patients with different clinical types of psoriasis using the 36-item short form of the Medical Outcomes Study questionnaire (SF-36), and to study its correlation with dermatology-specific instruments.
We conducted a cross-sectional study of 380 inpatients with psoriasis. SF-36 mean scores were compared with the norms for medical and psychiatric disorders. Quality of life was also measured by both dermatology-specific (Skindex-29 and Dermatology Life Quality Index, DLQI) and psoriasis-specific instruments (Psoriasis Disability Index, PDI, and the Impact of Psoriasis Questionnaire, IPSO). A specific (Psoriasis Life Stress Inventory, PLSI) and a generic (12-item General Health Questionnaire, GHQ-12) measure of psychological distress was also used. A cluster analysis was performed to study the relationship among the different questionnaires.
Our study population showed SF-36 physical health scores similar to minor medical conditions (e.g. physical functioning 79 for psoriasis, 80 for minor medical conditions, and 57 for severe medical conditions), but mental health scores quite similar to psychiatric illnesses (e.g. mental health 57 for psoriasis, 81 for minor medical conditions, 79 for severe medical conditions, and 53 for psychiatric conditions). The SF-36 showed two distinct patterns of impairment of quality of life, with a greater burden of disease for palmoplantar, pustular and arthropathic psoriasis. SF-36 scales tended to form separate clusters from the other dermatology-specific quality of life instruments.
A generic quality of life instrument (e.g. the SF-36) provides information that is complementary to that derived from dermatological questionnaires, and may give further insight in the evaluation of the burden of psoriasis.
在皮肤科领域，人们使用不同的特定和通用工具来评估生活质量，但它们之间的相互关系尚不为人所知。
使用医学结局研究问卷简表（SF - 36）描述不同临床类型银屑病患者的生活质量，并研究其与皮肤科特定工具的相关性。
我们对380例银屑病住院患者进行了横断面研究。将SF - 36平均得分与医学和精神疾病的常模进行比较。还通过皮肤科特定工具（Skindex - 29和皮肤病生活质量指数，DLQI）以及银屑病特定工具（银屑病残疾指数，PDI，和银屑病影响问卷，IPSO）来测量生活质量。还使用了一种特定的（银屑病生活压力量表，PLSI）和一种通用的（12项一般健康问卷，GHQ - 12）心理困扰测量工具。进行聚类分析以研究不同问卷之间的关系。
我们的研究人群显示，SF - 36身体健康得分与轻度医疗状况相似（例如，银屑病的身体功能得分为79，轻度医疗状况为80，重度医疗状况为57），但心理健康得分与精神疾病相当相似（例如，银屑病的心理健康得分为57，轻度医疗状况为81，重度医疗状况为79，精神疾病为53）。SF - 36显示出两种不同的生活质量受损模式，掌跖脓疱型和关节病型银屑病的疾病负担更大。SF - 36量表倾向于与其他皮肤科特定生活质量工具形成单独的聚类。
一种通用的生活质量工具（例如SF - 36）提供的信息与皮肤科问卷所获得的信息互补，并且可能在评估银屑病负担方面提供进一步的见解。
