Fikrle Tomas, Pizinger Karel
Department of Dermatology, Charles University, Pilsen, Czech Republic.
Dermatol Surg. 2005 Dec;31(12):1728-31. doi: 10.2310/6350.2005.31321.
Keloids are benign cutaneous lesions that result from excessive collagen synthesis and deposition. Earlobe keloids in particular are seen as a complication of plastic surgery or piercing. Many different treatment modalities have been used, often with unsatisfactory results.
We have made a retrospective analysis of seven young patients (ages 9 to 22 years) with earlobe keloids. Scarring followed plastic surgery in six cases and piercing in one case. All patients were treated with cryosurgery as the monotherapy. The freeze time and the number of sessions varied depending on the clinical findings, the effect of the treatment, and the patients' tolerance. Cryotherapy was started 6 to 24 months after keloid development.
Scar volume was reduced in all cases. Complete flattening in five patients and a pronounced reduction to a maximum of 25% of the previous thickness in one other patient were achieved. One patient discontinued the therapy because of soreness after only partial improvement. The procedure was painful for all patients; no further side effects were noticed. No recurrence was observed within 1 to 4.5 years of follow-up.
We present an excellent effect of cryosurgery as the monotherapy for the treatment of earlobe keloid scars of young patients.
瘢痕疙瘩是由胶原蛋白过度合成和沉积导致的良性皮肤病变。尤其是耳垂瘢痕疙瘩，常被视为整形手术或穿孔的并发症。人们使用了许多不同的治疗方法，但结果往往不尽人意。
我们对7例患有耳垂瘢痕疙瘩的年轻患者（年龄9至22岁）进行了回顾性分析。6例患者的瘢痕形成继发于整形手术，1例继发于穿孔。所有患者均接受冷冻手术作为单一疗法。冷冻时间和治疗次数根据临床发现、治疗效果和患者耐受性而有所不同。冷冻治疗在瘢痕疙瘩形成后6至24个月开始。
所有病例的瘢痕体积均减小。5例患者的瘢痕完全变平，另1例患者的瘢痕厚度明显减小，最大减小至先前厚度的25%。1例患者仅部分改善后因疼痛而停止治疗。该治疗方法对所有患者都有疼痛感；未观察到其他副作用。在1至4.5年的随访中未观察到复发。
我们展示了冷冻手术作为单一疗法治疗年轻患者耳垂瘢痕疙瘩的良好效果。
