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铒激光治疗后发疹性毳毛囊肿早期复发:病例报告及文献复习

Early recurrence of eruptive vellus hair cysts after Er:YAG laser therapy: case report and review of the literature.

作者信息

Coras Brigitte, Hohenleutner Ulrich, Landthaler Michael, Hohenleutner Silvia

机构信息

Department of Dermatology, University of Regensburg, Germany.

出版信息

Dermatol Surg. 2005 Dec;31(12):1741-4. doi: 10.2310/6350.2005.31325.

DOI:10.2310/6350.2005.31325
PMID:16336904
Abstract

BACKGROUND

Therapy of eruptive vellus hair cysts (EVHCs) often leads to unsatisfying results or recurrences. Recently, erbium:yttrium-aluminum-garnet (Er:YAG) laser therapy has been recommended in this condition.

OBJECTIVE

To report the results of Er:YAG laser treatment and discuss the treatment options in EVHC, presenting a review of the literature.

METHODS

Full-face Er:YAG laser therapy was performed in a 30-year-old female patient with a 15-year history of cosmetically bothersome facial EVHCs.

RESULTS

Immediately after the laser treatment, the ablated skin showed an even surface, presenting no residual signs of EVHCs. After reepithelialization, however, early recurrence of EVHCs occurred. Recurrence was also observed in the previously treated test spot, where slight atrophy indicated deeper ablation.

CONCLUSION

Er:YAG laser therapy might be a treatment option for distinct lesions of EVHCs but proved to be ineffective in a case of EVHCs in the face, where the depth of ablation is limited owing to the risk of atrophy or scarring and where deep enucleation of distinct single cysts was not possible owing to the dense dissemination of the lesions. Despite numerous treatment options reported in the literature, therapy for EVHCs is still challenging owing to recurrences or side effects.

摘要

背景

爆发性毳毛囊肿(EVHC)的治疗往往导致不尽人意的结果或复发。最近,铒:钇铝石榴石(Er:YAG)激光治疗被推荐用于这种情况。

目的

报告Er:YAG激光治疗的结果,并讨论EVHC的治疗选择,同时对文献进行综述。

方法

对一名30岁女性患者进行全面部Er:YAG激光治疗,该患者有15年因面部EVHC而影响美观的病史。

结果

激光治疗后立即观察到,消融后的皮肤表面平整,未残留EVHC迹象。然而,上皮再生后,EVHC早期复发。在先前治疗的测试部位也观察到复发,此处有轻微萎缩,表明消融较深。

结论

Er:YAG激光治疗可能是EVHC特定病变的一种治疗选择,但在面部EVHC病例中被证明无效,因为由于萎缩或瘢痕形成的风险,消融深度有限,且由于病变密集分布,无法对单个囊肿进行深部摘除。尽管文献报道了多种治疗选择,但由于复发或副作用,EVHC的治疗仍然具有挑战性。

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Low level laser therapy (LLLT) decreases pulmonary microvascular leakage, neutrophil influx and IL-1beta levels in airway and lung from rat subjected to LPS-induced inflammation.低强度激光疗法(LLLT)可减少脂多糖诱导炎症大鼠气道和肺部的肺微血管渗漏、中性粒细胞浸润及白细胞介素-1β水平。
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