Boëck-Neto Rodolfo Jorge, Gabrielli Mário Francisco Real, Shibli Jamil Awad, Marcantonio Elcio, Lia Raphael Carlos Comelli, Marcantonio Elcio
Department of Periodontology, Dental School at Araraquara, State University of São Paulo, UNESP, Araraquara, SP, Brazil.
Clin Implant Dent Relat Res. 2005;7(4):181-8. doi: 10.1111/j.1708-8208.2005.tb00063.x.
Prosthetic rehabilitation of the posterior maxilla with dental implants is often difficult because of proximity to the maxillary sinus and insufficient bone height. Maxillary sinus floor augmentation procedures aim to obtain enough bone with an association between biomaterials and autogenous bone.
The purpose of this study was to evaluate histomorphometrically two grafting materials (calcium phosphate and Ricinus communis polymer) used in maxillary sinus floor augmentation associated with autogenous bone.
Biopsies were taken from 10 consecutive subjects (mean age 45 years) 10 months after maxillary sinus floor augmentation. The sinus lift was performed with a mixture of autogenous bone and R. communis polymer or calcium phosphate in a 1:2 proportion. Routine histologic processing and staining with hematoxylin and eosin were performed.
The histomorphometric analysis indicated satisfactory regenerative results in both groups for a mean of bone tissue in the grafted area (44.24 +/- 13.79% for the calcium phosphate group and 38.77 +/- 12.85% for the polymer group). Histologic evaluation revealed the presence of an inflammatory infiltrate of mononuclear prevalence that, on average, was nonsignificant. The histologic sections depicted mature bone with compact and cancellous areas in both groups.
The results indicated that both graft materials associated with the autogenous bone were biocompatible, although both were still present after 10 months.
由于靠近上颌窦且骨高度不足，使用牙种植体对上颌后牙区进行修复通常很困难。上颌窦底提升术旨在通过生物材料与自体骨结合来获得足够的骨量。
本研究的目的是通过组织形态计量学评估用于上颌窦底提升并与自体骨联合使用的两种移植材料（磷酸钙和蓖麻聚合物）。
在上颌窦底提升术后10个月，对10名连续受试者（平均年龄45岁）进行活检。窦底提升采用自体骨与蓖麻聚合物或磷酸钙按1:2比例混合进行。进行常规组织学处理并用苏木精和伊红染色。
组织形态计量学分析表明，两组在移植区域的骨组织平均再生结果均令人满意（磷酸钙组为44.24±13.79%，聚合物组为38.77±12.85%）。组织学评估显示存在以单核细胞为主的炎性浸润，平均而言不显著。组织学切片显示两组均有成熟骨，包括致密骨和松质骨区域。
结果表明，与自体骨联合使用的两种移植材料均具有生物相容性，尽管在10个月后两种材料仍存在。
