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Neonatal handling reduces angiotensin II receptor density in the medial preoptic area and paraventricular nucleus but not in arcuate nucleus and locus coeruleus of female rats.

作者信息

Gomes Cármen Marilei, Donadio Márcio Vinícius Fagundes, Franskoviaki Inélia, Anselmo-Franci Janete A, Franci Celso Rodrigues, Lucion Aldo Bolten, Sanvitto Gilberto Luiz

机构信息

Departamento de Fisiologia, Instituto de Ciências Básicas da Saúde (ICBS), Universidade Federal do Rio Grande do Sul (UFRGS), Rua Sarmento Leite 500, Porto Alegre, RS 90050-170, Brazil.

出版信息

Brain Res. 2006 Jan 5;1067(1):177-80. doi: 10.1016/j.brainres.2005.10.081. Epub 2005 Dec 9.

DOI:10.1016/j.brainres.2005.10.081
PMID:16337927
Abstract

Neonatal handling alters the hypothalamic-pituitary-adrenal (HPA) axis and the hypothalamic-pituitary-gonads axis (HPG) in adult animals, and angiotensin II (Ang II) modulates the functions in these axes. We tested whether neonatal handling could change the density of Ang II receptors in some central areas in female rats. Results showed decreased density of the Ang II receptors in the medial preoptic area (MPOA) and hypothalamic paraventricular nucleus (PVN) of the neonatal handled group.

摘要

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