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Multiple heterotrimeric guanine nucleotide binding proteins: roles in the determination of cellular signalling specificity.

作者信息

Milligan G

机构信息

Department of Biochemistry, University of Glasgow, U.K.

出版信息

Biochem Soc Trans. 1992 Feb;20(1):135-40. doi: 10.1042/bst0200135.

DOI:10.1042/bst0200135
PMID:1633939
Abstract
摘要

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Multiple heterotrimeric guanine nucleotide binding proteins: roles in the determination of cellular signalling specificity.
Biochem Soc Trans. 1992 Feb;20(1):135-40. doi: 10.1042/bst0200135.
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Agonist activation of transfected human M1 muscarinic acetylcholine receptors in CHO cells results in down-regulation of both the receptor and the alpha subunit of the G-protein Gq.在CHO细胞中，转染的人M1毒蕈碱型乙酰胆碱受体的激动剂激活导致该受体和G蛋白Gq的α亚基均下调。
Biochem J. 1993 Jan 1;289 ( Pt 1)(Pt 1):125-31. doi: 10.1042/bj2890125.
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Calcium: its modulation in liver by cross-talk between the actions of glucagon and calcium-mobilizing agonists.钙：胰高血糖素与钙动员激动剂作用之间的相互作用对其在肝脏中的调节
Biochem J. 1993 Nov 15;296 ( Pt 1)(Pt 1):1-14. doi: 10.1042/bj2960001.
3
N-terminal fatty acylation of the alpha-subunit of the G-protein Gi1: only the myristoylated protein is a substrate for palmitoylation.
G蛋白Gi1的α亚基的N端脂肪酰化：只有肉豆蔻酰化的蛋白是棕榈酰化的底物。
Biochem J. 1994 Nov 1;303 ( Pt 3)(Pt 3):697-700. doi: 10.1042/bj3030697.