Peel Andrew D, Chipman Ariel D, Akam Michael
University Museum of Zoology, Department of Zoology, Downing Street, Cambridge CB2 3EJ, UK.
Nat Rev Genet. 2005 Dec;6(12):905-16. doi: 10.1038/nrg1724.
Most of our knowledge about the mechanisms of segmentation in arthropods comes from work on Drosophila melanogaster. In recent years it has become clear that this mechanism is far from universal, and different arthropod groups have distinct modes of segmentation that operate through divergent genetic mechanisms. We review recent data from a range of arthropods, identifying which features of the D. melanogaster segmentation cascade are present in the different groups, and discuss the evolutionary implications of their conserved and divergent aspects. A model is emerging, although slowly, for the way that arthropod segmentation mechanisms have evolved.
我们关于节肢动物体节形成机制的大部分知识来自对黑腹果蝇的研究。近年来，很明显这种机制远非普遍适用，不同的节肢动物类群具有不同的体节形成模式，这些模式通过不同的遗传机制发挥作用。我们回顾了一系列节肢动物的最新数据，确定黑腹果蝇体节形成级联反应的哪些特征存在于不同类群中，并讨论其保守和不同方面的进化意义。尽管进展缓慢，但关于节肢动物体节形成机制如何进化的模型正在浮现。
