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Genome science: a video tour of the Washington University Genome Sequencing Center for high school and undergraduate students.基因组科学:面向高中生和本科生的华盛顿大学基因组测序中心视频之旅。
Cell Biol Educ. 2005 Winter;4(4):291-7. doi: 10.1187/cbe.05-07-0088.
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Whole genome sequencing in the undergraduate classroom: outcomes and lessons from a pilot course.本科课堂中的全基因组测序:试点课程的成果与经验教训。
J Microbiol Biol Educ. 2008 Dec 17;9(1):3-11. Print 2008.

本文引用的文献

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An inquiry into protein structure and genetic disease: introducing undergraduates to bioinformatics in a large introductory course.对蛋白质结构与遗传疾病的探究:在大型入门课程中向本科生介绍生物信息学
Cell Biol Educ. 2005 Fall;4(3):207-20. doi: 10.1187/cbe.04-07-0044.
2
Genome sequencing in microfabricated high-density picolitre reactors.微制造高密度皮升反应器中的基因组测序
Nature. 2005 Sep 15;437(7057):376-80. doi: 10.1038/nature03959. Epub 2005 Jul 31.
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Shaping science policy in the age of genomics.基因组学时代的科学政策塑造
Nat Rev Genet. 2004 Apr;5(4):311-6. doi: 10.1038/nrg1320.
4
Public access for teaching genomics, proteomics, and bioinformatics.用于教学基因组学、蛋白质组学和生物信息学的公共访问。
Cell Biol Educ. 2003 Summer;2(2):98-111. doi: 10.1187/cbe.03-02-0007.
5
Implications of the human genome for understanding human biology and medicine.人类基因组对于理解人类生物学和医学的意义。
JAMA. 2001 Nov 14;286(18):2296-307. doi: 10.1001/jama.286.18.2296.
6
Human genetics on the web.网络上的人类遗传学。
Annu Rev Genomics Hum Genet. 2001;2:213-33. doi: 10.1146/annurev.genom.2.1.213.
7
The Ethical, Legal, and Social Implications Research Program at the National Human Genome Research Institute.国家人类基因组研究所的伦理、法律和社会影响研究项目。
Kennedy Inst Ethics J. 1997 Sep;7(3):291-8. doi: 10.1353/ken.1997.0025.
8
Implications of the Human Genome Project for medical science.人类基因组计划对医学科学的影响。
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基因组科学:面向高中生和本科生的华盛顿大学基因组测序中心视频之旅。

Genome science: a video tour of the Washington University Genome Sequencing Center for high school and undergraduate students.

作者信息

Flowers Susan K, Easter Carla, Holmes Andrea, Cohen Brian, Bednarski April E, Mardis Elaine R, Wilson Richard K, Elgin Sarah C R

机构信息

Department of Biology, Washington University, St. Louis, MO 63130, USA.

出版信息

Cell Biol Educ. 2005 Winter;4(4):291-7. doi: 10.1187/cbe.05-07-0088.

DOI:10.1187/cbe.05-07-0088
PMID:16341256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1305891/
Abstract

Sequencing of the human genome has ushered in a new era of biology. The technologies developed to facilitate the sequencing of the human genome are now being applied to the sequencing of other genomes. In 2004, a partnership was formed between Washington University School of Medicine Genome Sequencing Center's Outreach Program and Washington University Department of Biology Science Outreach to create a video tour depicting the processes involved in large-scale sequencing. "Sequencing a Genome: Inside the Washington University Genome Sequencing Center" is a tour of the laboratory that follows the steps in the sequencing pipeline, interspersed with animated explanations of the scientific procedures used at the facility. Accompanying interviews with the staff illustrate different entry levels for a career in genome science. This video project serves as an example of how research and academic institutions can provide teachers and students with access and exposure to innovative technologies at the forefront of biomedical research. Initial feedback on the video from undergraduate students, high school teachers, and high school students provides suggestions for use of this video in a classroom setting to supplement present curricula.

摘要

人类基因组测序开创了生物学的新纪元。为推动人类基因组测序而开发的技术,如今正应用于其他基因组的测序。2004年,华盛顿大学医学院基因组测序中心外展项目与华盛顿大学生物科学外展系合作,制作了一段视频,展示大规模测序所涉及的过程。《基因组测序:走进华盛顿大学基因组测序中心》是一次实验室之旅,它按照测序流程的步骤进行展示,并穿插对该设施所使用科学程序的动画解释。对工作人员的访谈展示了基因组科学领域不同的职业入门级别。这个视频项目展示了研究机构和学术机构如何为教师和学生提供接触生物医学前沿创新技术的机会。本科生、高中教师和高中生对该视频的初步反馈,为在课堂上使用此视频以补充现有课程提供了建议。