Murialdo R, Usset A, Guido T, Carli F, Boccardo F, Amoroso D
Department of Medical Oncology B, National Institute for Cancer Research, Genova, Italy.
Int J Gynecol Cancer. 2005 Nov-Dec;15(6):1226-9. doi: 10.1111/j.1525-1438.2005.00176.x.
Leiomyosarcoma of the broad ligament is a rare tumor, since only 12 cases have been reported so far in the literature. A 53-year-old patient was diagnosed with leiomyosarcoma of the broad ligament at the Department of Gynecology Oncology of the National Cancer Research Institute in Genoa. The tumor had low mitotic activity and less than ten mitotic figures were found for ten high-power fields. The treatment consisted of total abdominal hysterectomy and bilateral salpingo-oophorectomy with bilateral ureteral neoanastomosis and omentectomy. The patient has not received either radiotherapy or chemotherapy, considering the low grade of malignancy, but she is only followed up on an outpatient basis. No evidence of metastasis has been noted after a follow-up of 13 months. It is concluded that low-grade leiomyosarcoma of the broad ligament should be treated only with surgery.
阔韧带平滑肌肉瘤是一种罕见的肿瘤,因为迄今为止文献中仅报道了12例。一名53岁的患者在热那亚国家癌症研究所妇科肿瘤学部门被诊断为阔韧带平滑肌肉瘤。该肿瘤有丝分裂活性低,在十个高倍视野中发现的有丝分裂象少于十个。治疗包括全腹子宫切除术、双侧输卵管卵巢切除术、双侧输尿管新吻合术和网膜切除术。考虑到恶性程度低,该患者未接受放疗或化疗,仅在门诊进行随访。随访13个月后未发现转移迹象。结论是,阔韧带低度平滑肌肉瘤仅应采用手术治疗。