Kolusari A, Ugurluer G, Kosem M, Kurdoglu M, Yildizhan R, Adali E
Department of Obstetrics and Gynaecology, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey.
Eur J Gynaecol Oncol. 2009;30(3):332-4.
Leiomyosarcoma of the broad ligament is a rare tumour, since only 15 cases have been reported thus far in the English literature. We describe the case of a 35-year-old patient with primary leiomyosarcoma of the broad ligament. The histologic diagnosis and management of this rapidly progressive and highly malignant tumour are also discussed. The tumor had high mitotic activity and more than ten mitotic figures were found for ten high-power fields. The treatment consisted of total abdominal hysterectomy, bilateral salpingo-oophorectomy and pelvic lymph node dissection. The patient received pelvic radiotherapy and chemotherapy considering the high grade of malignancy. No evidence of metastasis has been noted after a follow-up of 12 months.
阔韧带平滑肌肉瘤是一种罕见的肿瘤，因为迄今为止英文文献中仅报道了15例。我们描述了一名35岁患有原发性阔韧带平滑肌肉瘤患者的病例。还讨论了这种快速进展且高度恶性肿瘤的组织学诊断和治疗方法。该肿瘤有高有丝分裂活性，在十个高倍视野中发现了十多个有丝分裂象。治疗包括全腹子宫切除术、双侧输卵管卵巢切除术和盆腔淋巴结清扫术。鉴于恶性程度高，患者接受了盆腔放疗和化疗。随访12个月后未发现转移迹象。
