Kanaoka Yasushi, Hirai Kouzo, Ishiko Osamu
Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine, Osaka, Japan.
J Obstet Gynaecol Res. 2005 Dec;31(6):565-70. doi: 10.1111/j.1447-0756.2005.00338.x.
To examine the feasibility of microwave endometrial ablation (MEA), using a curved microwave applicator, in patients with menorrhagia caused by a submucous myoma greater than 3 cm in diameter, which is among the contraindications for conventional endometrial ablation.
Patients included were refractory to medication, more than 45 years of age, and due to undergo hysterectomy to treat menorrhagia as a result of submucous myomas, although they hoped to avoid hysterectomy. Three patients underwent MEA at 2.45 GHz using a curved microwave applicator and microwave tissue coagulator to treat menorrhagia. Patients 1, 2 and 3 had submucous myoma nodes 4.5, 5.0 and 13 cm in diameter respectively. The applicator was guided under transabdominal ultrasonography to microwave irradiation sites arranged to cover the entire uterine lining based on preoperative magnetic resonance images. MEA was performed under general anesthesia or spinal anesthesia. Microwaves were irradiated at 40 W for 50 s for single irradiation sites.
Patient 1 became amenorrheic after the second MEA, which was performed 2 months after the first operation. Patients 2 and 3 became amenorrheic after the first MEA. Postoperative abdominal pain was controllable by a suppository of non-steroidal anti-inflammatory drugs. The patients were discharged the day after the operation. No remarkable complications were encountered during or after surgery.
Microwave endometrial ablation improves menorrhagia caused by large submucous myomas when the microwave applicator reaches all parts of the uterine cavity.
探讨使用弯曲微波施源器进行微波子宫内膜消融术(MEA)治疗直径大于3 cm的黏膜下肌瘤所致月经过多的可行性,而这在传统子宫内膜消融术的禁忌证中。
纳入的患者药物治疗无效、年龄超过45岁,因黏膜下肌瘤导致月经过多原本要接受子宫切除术,但她们希望避免子宫切除。3例患者使用弯曲微波施源器和微波组织凝固器在2.45 GHz频率下进行MEA以治疗月经过多。患者1、2和3的黏膜下肌瘤结节直径分别为4.5、5.0和13 cm。在经腹超声引导下,根据术前磁共振图像将施源器引导至覆盖整个子宫内膜的微波照射部位。MEA在全身麻醉或脊髓麻醉下进行。单照射部位以40 W照射50 s。
患者1在首次手术后2个月进行第二次MEA后闭经。患者2和3在首次MEA后闭经。术后腹痛可用非甾体类抗炎药栓剂控制。患者术后次日出院。手术期间及术后未出现明显并发症。
当微波施源器到达子宫腔各部位时,微波子宫内膜消融术可改善由大型黏膜下肌瘤引起的月经过多。