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微波子宫内膜切除术治疗巨大黏膜下肌瘤所致月经过多

Microwave endometrial ablation for menorrhagia caused by large submucous myomas.

作者信息

Kanaoka Yasushi, Hirai Kouzo, Ishiko Osamu

机构信息

Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine, Osaka, Japan.

出版信息

J Obstet Gynaecol Res. 2005 Dec;31(6):565-70. doi: 10.1111/j.1447-0756.2005.00338.x.

DOI:10.1111/j.1447-0756.2005.00338.x
PMID:16343261
Abstract

AIM

To examine the feasibility of microwave endometrial ablation (MEA), using a curved microwave applicator, in patients with menorrhagia caused by a submucous myoma greater than 3 cm in diameter, which is among the contraindications for conventional endometrial ablation.

METHODS

Patients included were refractory to medication, more than 45 years of age, and due to undergo hysterectomy to treat menorrhagia as a result of submucous myomas, although they hoped to avoid hysterectomy. Three patients underwent MEA at 2.45 GHz using a curved microwave applicator and microwave tissue coagulator to treat menorrhagia. Patients 1, 2 and 3 had submucous myoma nodes 4.5, 5.0 and 13 cm in diameter respectively. The applicator was guided under transabdominal ultrasonography to microwave irradiation sites arranged to cover the entire uterine lining based on preoperative magnetic resonance images. MEA was performed under general anesthesia or spinal anesthesia. Microwaves were irradiated at 40 W for 50 s for single irradiation sites.

RESULTS

Patient 1 became amenorrheic after the second MEA, which was performed 2 months after the first operation. Patients 2 and 3 became amenorrheic after the first MEA. Postoperative abdominal pain was controllable by a suppository of non-steroidal anti-inflammatory drugs. The patients were discharged the day after the operation. No remarkable complications were encountered during or after surgery.

CONCLUSION

Microwave endometrial ablation improves menorrhagia caused by large submucous myomas when the microwave applicator reaches all parts of the uterine cavity.

摘要

目的

探讨使用弯曲微波施源器进行微波子宫内膜消融术(MEA)治疗直径大于3 cm的黏膜下肌瘤所致月经过多的可行性,而这在传统子宫内膜消融术的禁忌证中。

方法

纳入的患者药物治疗无效、年龄超过45岁,因黏膜下肌瘤导致月经过多原本要接受子宫切除术,但她们希望避免子宫切除。3例患者使用弯曲微波施源器和微波组织凝固器在2.45 GHz频率下进行MEA以治疗月经过多。患者1、2和3的黏膜下肌瘤结节直径分别为4.5、5.0和13 cm。在经腹超声引导下,根据术前磁共振图像将施源器引导至覆盖整个子宫内膜的微波照射部位。MEA在全身麻醉或脊髓麻醉下进行。单照射部位以40 W照射50 s。

结果

患者1在首次手术后2个月进行第二次MEA后闭经。患者2和3在首次MEA后闭经。术后腹痛可用非甾体类抗炎药栓剂控制。患者术后次日出院。手术期间及术后未出现明显并发症。

结论

当微波施源器到达子宫腔各部位时,微波子宫内膜消融术可改善由大型黏膜下肌瘤引起的月经过多。

相似文献

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Microwave endometrial ablation for menorrhagia caused by large submucous myomas.微波子宫内膜切除术治疗巨大黏膜下肌瘤所致月经过多
J Obstet Gynaecol Res. 2005 Dec;31(6):565-70. doi: 10.1111/j.1447-0756.2005.00338.x.
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Office endometrial ablation with local anesthesia using the HydroThermAblator system: Comparison of outcomes in patients with submucous myomas with those with normal cavities in 246 cases performed over 5(1/2) years.在 5 年半的时间里,对 246 例患者进行了局部麻醉下的 HydroThermAblator 系统宫腔镜子宫内膜切除术:比较黏膜下肌瘤患者与正常宫腔患者的结局。
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Transcervical microwave myolysis for uterine myomas assisted by transvaginal ultrasonic guidance.经阴道超声引导下经宫颈微波消融治疗子宫肌瘤
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Outpatient transcervical microwave myolysis assisted by transabdominal ultrasonic guidance for menorrhagia caused by submucosal myomas.经腹超声引导下门诊经宫颈微波消融术治疗黏膜下肌瘤所致月经过多
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[Tissue injury observation caused by thermal effects of microwave endometrial ablation].[微波子宫内膜消融热效应引起的组织损伤观察]
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The safety and efficacy of microwave endometrial ablation after endometrial curettage without hormonal pretreatment.子宫内膜刮除术后未经激素预处理的微波子宫内膜切除术的安全性和有效性。
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Microwave endometrial ablation as an alternative to hysterectomy for the emergent control of uterine bleeding in patients who are poor surgical candidates.对于手术风险高的患者,微波子宫内膜消融术可作为子宫切除术的替代方法,用于紧急控制子宫出血。
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