Loghin Monica, Levin Victor A
Neuro-Oncology Unit 431, UT MD Anderson Cancer Center, PO Box 301402, Houston, TX 77230, USA.
Curr Treat Options Neurol. 2006 Jan;8(1):21-32. doi: 10.1007/s11940-996-0021-y.
Headache is one of the most common somatic complaints of patients seeking medical care. Most headaches are not of serious cause and can be diagnosed easily with a good history and physical examination. The challenges to the physician are to determine when underlying intracranial pathology may be causing the symptoms and signs, and to identify the few patients in whom a tumor is the cause of the headache. The subject of headache in patients with brain tumors has been reviewed in neurologic textbooks and in several investigations before, as well as after, modern imaging diagnostic techniques became available. Headache can also manifest as an acute or chronic complication of radiation treatment and/or chemotherapy in patients with intracranial neoplasm, but there are few data in the literature specifically addressing this subject. This article provides an overview of headache in patients with primary and secondary brain tumor, including headache characteristics, the putative mechanism for these headaches, the role of diagnostic testing, and the general principles of management.
头痛是就医患者最常见的躯体不适之一。大多数头痛并非由严重病因引起，通过详细的病史询问和体格检查即可轻松诊断。对医生而言，挑战在于确定何时潜在的颅内病变可能导致症状和体征，并识别出少数由肿瘤引起头痛的患者。在现代影像诊断技术出现之前和之后，神经学教科书及多项研究都对脑肿瘤患者的头痛问题进行过综述。头痛也可表现为颅内肿瘤患者放疗和/或化疗的急性或慢性并发症，但文献中专门针对这一主题的数据较少。本文概述了原发性和继发性脑肿瘤患者的头痛情况，包括头痛特点、这些头痛的推测机制、诊断检查的作用以及一般治疗原则。
