Andreozzi R, Caprio V, Di Somma I, Sanchirico R
Università di Napoli Federico II, p.le V. Tecchio, 80-80125 Napoli, Italy.
J Hazard Mater. 2006 Jun 30;134(1-3):1-7. doi: 10.1016/j.jhazmat.2005.10.037. Epub 2005 Dec 15.
The nitration process of salicylic acid for the production of the important intermediate 5-nitrosalicylic acid is studied from thermokinetic and safety points of view. Investigations carried out by considering, as process deviations, the loss of the thermal control point out the possibility of runaway phenomena due to the occurrence of polynitration reactions. Isothermal experiments are carried out in various conditions to assess the involved reaction network and reaction kinetics.
从热动力学和安全角度研究了用于生产重要中间体5-硝基水杨酸的水杨酸硝化过程。通过将热控制点的损失视为过程偏差进行的研究指出，由于多硝化反应的发生，存在失控现象的可能性。在各种条件下进行等温实验，以评估所涉及的反应网络和反应动力学。
