Martinez J E, Mohiaddin R H, Kilner P J, Khaw K, Rees S, Somerville J, Longmore D B
Grown up Congenital Heart Unit, Royal Brompton National Heart and Lung Hospital, Chelsea.
J Am Coll Cardiol. 1992 Aug;20(2):338-44. doi: 10.1016/0735-1097(92)90099-9.
This study was designed to investigate the value of noninvasive imaging modalities for the detection of obstruction in extracardiac ventriculopulmonary conduits.
the diagnosis of obstruction in a conduit by noninvasive methods can be difficult. Obstruction may be silent and its progression unnoticed. Nuclear magnetic resonance imaging (NMR) with velocity mapping is a new noninvasive technique that can provide high resolution images and has been shown to be a reliable method of measuring blood flow velocity.
Two-dimensional echocardiography, pulsed wave Doppler echocardiography and NMR spin echo imaging were used in 52 patients with an extracardiac ventriculopulmonary conduit. Continuous wave Doppler echocardiography was used in 30 of these, Doppler color flow mapping in 26 and NMR velocity mapping in 12. Cardiac catheterization data were available in 27 patients and operative or autopsy findings in 11.
The conduit could be assessed by two-dimensional and pulsed wave Doppler echocardiography in only 17% of patients. Doppler color flow and continuous wave echocardiography provided technically satisfactory data in 19% and 83%, respectively. The anatomy of the conduit was adequately displayed by NMR imaging in 90%. A minimal diameter less than 18 mm indicated conduit obstruction, although failure to detect calcification resulted in obstruction being missed in some patients. Calculated gradients in obstructed conduits derived from NMR velocity mapping correlated well with results of continuous wave Doppler echocardiography and gave an accurate localization of the site of obstruction as well as a measure of its severity.
NMR imaging with velocity mapping is the most effective noninvasive method of assessing obstruction in ventriculopulmonary conduits and can obviate the need for invasive investigation before an interventional procedure is performed.
本研究旨在探讨无创成像方式对检测心外心室 - 肺导管梗阻的价值。
通过无创方法诊断导管梗阻可能具有挑战性。梗阻可能无症状,其进展未被察觉。带有流速映射的核磁共振成像(NMR)是一种新的无创技术,可提供高分辨率图像,并且已被证明是测量血流速度的可靠方法。
对52例患有心外心室 - 肺导管的患者使用二维超声心动图、脉冲波多普勒超声心动图和NMR自旋回波成像。其中30例使用连续波多普勒超声心动图,26例使用彩色多普勒血流图,12例使用NMR流速映射。27例患者有心脏导管检查数据,11例有手术或尸检结果。
仅17%的患者可通过二维和脉冲波多普勒超声心动图评估导管。彩色多普勒血流图和连续波超声心动图分别在19%和83%的患者中提供了技术上令人满意的数据。90%的患者通过NMR成像充分显示了导管的解剖结构。最小直径小于18 mm提示导管梗阻,尽管未能检测到钙化导致部分患者的梗阻被漏诊。从NMR流速映射得出的梗阻导管的计算梯度与连续波多普勒超声心动图的结果相关性良好,可准确确定梗阻部位并衡量其严重程度。
带有流速映射的NMR成像是评估心室 - 肺导管梗阻最有效的无创方法,可避免在进行介入手术前进行有创检查。