Lachs M S, Becker M, Siegal A P, Miller R L, Tinetti M E
Department of Medicine, Yale University School of Medicine, New Haven, CT.
J Am Geriatr Soc. 1992 Aug;40(8):768-73. doi: 10.1111/j.1532-5415.1992.tb01847.x.
To compare cognitive function and the prevalence of selected behavioral problems in delusional and non-delusional dementia patients.
Retrospective medical record review.
An outpatient geriatric assessment center.
114 consecutive patients with dementia.
Delusions as recorded in a consultation report.
Delusions were described in 25.5% of patients. A variety of behavioral disturbances were more common in delusional than non-delusional patients, including agitation, angry or hostile outbursts, urinary incontinence, wandering or pacing, and insomnia. While cognitive function as measured by the MMSE was similar in delusional and non-delusional patients (18.9 +/- 3.8 and 19.2 +/- 5.9, respectively), there was a statistically borderline tendency for delusions to occur more often in patients in the mid-range of cognitive impairment (17 less than or equal to MMSE less than or equal to 23) compared with patients with greater or lesser degrees of cognitive impairment (32% vs 17% respectively).
Delusions in dementia are associated with a variety of behavioral problems. Further studies are needed to clarify the role of delusions in the development of disruptive behaviors in dementing illness.
比较妄想性痴呆患者与非妄想性痴呆患者的认知功能及特定行为问题的发生率。
回顾性病历审查。
门诊老年评估中心。
114例连续性痴呆患者。
会诊报告中记录的妄想。
25.5%的患者存在妄想。与非妄想性患者相比,妄想性患者出现的各种行为障碍更为常见,包括激越、愤怒或敌对发作、尿失禁、徘徊或踱步以及失眠。虽然通过简易精神状态检查表(MMSE)测量的认知功能在妄想性患者和非妄想性患者中相似(分别为18.9±3.8和19.2±5.9),但与认知障碍程度较高或较低的患者相比(分别为32%和17%),在认知障碍处于中等范围(17≤MMSE≤23)的患者中,妄想出现的频率在统计学上有临界倾向。
痴呆中的妄想与多种行为问题相关。需要进一步研究以阐明妄想在痴呆性疾病破坏性行为发展中的作用。