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[一例小胸腺瘤合并重症肌无力,经皮质类固醇治疗后肿瘤缩小]

[A case of a small thymoma associated with myasthenia gravis in which the tumor was reduced by corticosteroid therapy].

作者信息

Mizuno T, Hashimoto T, Yamakawa Y, Niwa H, Masaoka A

机构信息

Second Department of Surgery, Nagoya City University Medical School, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1992 Jun;40(6):975-7.

PMID:1634847
Abstract

The case in this study was a 34-year-old male with a small thymoma associated with myasthenia gravis. The patient had been treated with corticosteroids for 10 months against myasthenia gravis. During the course of the treatment a chest CT revealed that the tumor had reduced. Thereafter the extended thymectomy was performed. A close examination of the excised thymus revealed the presence of a flat cystic tumor measuring 1.5 x 0.8 x 0.5 cm at the site corresponding to the CT image. This tumor was histologically ascertained to be a thymoma. The thymoma is sensitive to corticosteroids, which can effectively reduce it. As conclusion, it is necessary to check thoroughly on the presence of thymoma prior to the initiation of corticosteroid therapy to treat myasthenia gravis.

摘要

本研究中的病例是一名34岁男性,患有与重症肌无力相关的小胸腺瘤。该患者已针对重症肌无力接受了10个月的皮质类固醇治疗。在治疗过程中,胸部CT显示肿瘤缩小。此后进行了扩大胸腺切除术。对切除的胸腺进行仔细检查发现,在与CT图像对应的部位存在一个扁平囊性肿瘤,大小为1.5×0.8×0.5厘米。该肿瘤经组织学确定为胸腺瘤。胸腺瘤对皮质类固醇敏感,皮质类固醇可有效缩小肿瘤。总之,在开始使用皮质类固醇治疗重症肌无力之前,有必要彻底检查是否存在胸腺瘤。

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