Poenitz Nina, Tadler Dorothea, Klemke Claus-Detlev, Glorer Elke, Goerdt Sergij
Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Mannheim, Ruprecht-Karls-Universität Heidelberg, Mannheim.
J Dtsch Dermatol Ges. 2005 Feb;3(2):113-6. doi: 10.1111/j.1610-0378.2005.04746.x.
Pyoderma gangrenosum is a chronic, noninfectious, ulcerating cutaneous disease of unknown etiology usually presenting with multiple lesions on the legs and trunk. Solitary lesions in other locations are rare and therefore hard to diagnose. A 78-year-old and a 81-year-old woman with extensive scalp necrosis were both diagnosed as pyoderma gangrenosum after exclusion of other differential diagnostic possibilities. The separate diagnosis of malignant pyoderma for this disease state no longer seems justified. Scalp necrosis is infrequently seen in dermatological patients; most previous reports describe it in giant cell arteritis. Other differential diagnoses include viral, bacterial and mycotic infections as well as erosive pustular dermatosis of the scalp. In conclusion, we again draw attention to unilesional pyoderma gangrenosum of the scalp as a rare disease entity. Immunosuppressive drugs are an effective treatment modality.
坏疽性脓皮病是一种病因不明的慢性、非感染性、溃疡性皮肤病，通常在腿部和躯干出现多处皮损。其他部位的孤立性皮损罕见，因此难以诊断。一名78岁和一名81岁的女性出现广泛的头皮坏死，在排除其他鉴别诊断可能性后均被诊断为坏疽性脓皮病。对于这种疾病状态，单独诊断为恶性脓皮病似乎不再合理。头皮坏死在皮肤科患者中很少见；既往大多数报道是在巨细胞动脉炎中描述。其他鉴别诊断包括病毒、细菌和真菌感染以及头皮糜烂性脓疱性皮肤病。总之，我们再次提请注意头皮单发性坏疽性脓皮病这一罕见的疾病实体。免疫抑制药物是一种有效的治疗方式。
