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广泛的、不愈合的头皮溃疡,与创伤性慢性骨髓炎相关。

Extensive, non-healing scalp ulcer associated with trauma-induced chronic osteomyelitis.

作者信息

Valerón-Almazán Pedro, Gómez-Duaso Anselmo Javier, Rivero Pino, Vilar Jaime, Dehesa Luis, Santana Néstor, Carretero Gregorio

机构信息

Service of Dermatology, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain.

出版信息

Ann Dermatol. 2011 Dec;23(Suppl 3):S364-7. doi: 10.5021/ad.2011.23.S3.S364. Epub 2011 Dec 27.

Abstract

A 77-year-old woman presented with a trauma to the scalp caused from the blade of a windmill. The condition was persistent from the past 50 years. At the initial examination, a deep, foul-smelling and well-circumscribed ulcer was apparent on the head region, involving the majority of the cranium. Skin biopsy specimens of the lesion were nonspecific. The bone biopsy showed extensive necrotic areas of bone and soft tissues, with lymphocytic exudate foci. A computed tomography scan of the head revealed bone destruction principally involving both the parietal bones, and parts of the frontal and occipital bones. Streptococcus parasanguis was isolated from the skin culture, and Proteus mirabilis and Peptostreptococcus sp. were identified in the cultures from the bone. A long-term treatment with amoxicillin-clavulanic acid (1 g/12 h) and levofloxacin (500 mg/day) was prescribed, but even after 6 months, the lesion remained unchanged. The frequency of occurrence of scalp ulcers in dermatological patients is less, principally because of the rich blood supply to this area. We have not found any similar case report of a scalp ulcer secondary to chronic osteomyelitis discovered more than 50 years after the causal trauma. We want to highlight the importance of complete cutaneous evaluation including skin and bone biopsies, when scalp osteomyelitis is suspected.

摘要

一名77岁女性因风车叶片导致头皮外伤。这种情况已持续50年。初次检查时,头部可见一个深的、有恶臭且边界清晰的溃疡,累及大部分颅骨。病变的皮肤活检标本无特异性。骨活检显示骨和软组织有广泛坏死区域,伴有淋巴细胞渗出灶。头部计算机断层扫描显示骨质破坏主要累及双侧顶骨以及部分额骨和枕骨。从皮肤培养物中分离出副血链球菌,从骨培养物中鉴定出奇异变形杆菌和消化链球菌属。给予阿莫西林 - 克拉维酸(1克/12小时)和左氧氟沙星(500毫克/天)长期治疗,但即使6个月后,病变仍无变化。皮肤科患者头皮溃疡的发生率较低,主要是因为该区域血液供应丰富。我们未发现任何关于因果创伤50多年后发现的慢性骨髓炎继发头皮溃疡的类似病例报告。我们想强调,当怀疑头皮骨髓炎时,包括皮肤和骨活检在内的完整皮肤评估的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0b8/3276798/38046c061bdf/ad-23-S364-g001.jpg

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