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肛门闭锁青少年神经源性膀胱的管理

The management of the neuropathic bladder in adolescents with imperforate anus.

作者信息

Ralph D J, Woodhouse C R, Ransley P G

机构信息

Institute of Urology, Hospital for Sick Children, London, England.

出版信息

J Urol. 1992 Aug;148(2 Pt 1):366-8. doi: 10.1016/s0022-5347(17)36598-9.

Abstract

The management of 58 patients born with an imperforate anus who presented to the urology service and who are currently 18 years old or older is discussed. Of the 44 patients with a high imperforate anus 43 were treated by a rectal pull-through and 1 by an anal cut back procedure, while an anal cut back procedure was used in all 14 children with a low imperforate anus. A total of 32 children (55%) had a neuropathic bladder (hyperreflexic in 29 and atonic in 3). A spinal deformity was present in 72% of the hyperreflexic group but not in the atonic group. Vesicoureteral reflux occurred in 41% of the patients, two-thirds of whom had a neuropathic bladder. A total of 30 children had an associated genital anomaly and 27 had an upper tract anomaly. Nineteen children underwent an operation for the neuropathic bladder, with modern reconstructive methods involving substitution or augmentation cystoplasty, supplemented with self-catheterization, being superior to older methods with regard to continence. The incidence of a neuropathic bladder in these children is high in both operative groups but it is usually associated with a spinal deformity and unlikely to be iatrogenic in nature unless proved to be of lower motor neuron origin. Early operative management is advised to achieve continence and minimize renal impairment.

摘要

本文讨论了58例出生时患有肛门闭锁且前来泌尿外科就诊、目前年龄在18岁及以上患者的治疗情况。在44例高位肛门闭锁患者中,43例行直肠拖出术,1例行肛门后切术;而14例低位肛门闭锁患儿均采用肛门后切术。共有32例患儿(55%)存在神经源性膀胱(其中29例为反射亢进型,3例为无张力型)。反射亢进型患儿中有72%存在脊柱畸形,无张力型患儿则无。41%的患者发生膀胱输尿管反流,其中三分之二有神经源性膀胱。共有30例患儿合并生殖器官异常,27例合并上尿路异常。19例患儿因神经源性膀胱接受手术,采用替代或扩大膀胱成形术等现代重建方法并辅以自我导尿,在控尿方面优于传统方法。在这两个手术组中,这些患儿神经源性膀胱的发生率都很高,但通常与脊柱畸形有关,除非证明是下运动神经元起源,否则不太可能是医源性的。建议早期进行手术治疗以实现控尿并尽量减少肾功能损害。

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