一名免疫功能正常的年轻男性在初次感染非典型弓形虫菌株期间发生严重肺炎。

Severe pneumonia during primary infection with an atypical strain of Toxoplasma gondii in an immunocompetent young man.

作者信息

De Salvador-Guillouët Francine, Ajzenberg Daniel, Chaillou-Opitz Sylvie, Saint-Paul Marie-Christine, Dunais Brigitte, Dellamonica Pierre, Marty Pierre

机构信息

Centre Hospitalier-Universitaire de Nice, Service d'Infectiologie, Hôpital de l'Archet, BP 3079 06202--Nice Cedex 3, France.

出版信息

J Infect. 2006 Aug;53(2):e47-50. doi: 10.1016/j.jinf.2005.10.026. Epub 2005 Dec 15.

DOI:10.1016/j.jinf.2005.10.026

PMID:16352339

Abstract

We report a case of severe acute primary pulmonary toxoplasmosis in an immunocompetent young man living in Nice (Southern France). The Toxoplasma DNA extracted from the broncho-alveolar lavage fluid allowed a genetic characterization of the responsible strain which displayed an atypical genotype of Toxoplasma gondii. This unusual genetic composition of the parasite may have influenced, among other factors, the severity of the disease.

摘要

我们报告了一例居住在法国南部尼斯的免疫功能正常的年轻男性患严重急性原发性肺弓形虫病的病例。从支气管肺泡灌洗液中提取的弓形虫DNA对致病菌株进行了基因特征分析，该菌株显示出一种非典型的刚地弓形虫基因型。除其他因素外，这种寄生虫不寻常的基因组成可能影响了疾病的严重程度。