Huang Junmin, Li Tingyu
Department of Chemistry, Box 9573, Mississippi State University, Mississippi State, Mississippi 39762, USA.
Org Lett. 2005 Dec 22;7(26):5821-3. doi: 10.1021/ol052309z.
[graph: see text] Separation factors as high as 115 were observed for the chromatographic resolution of many alpha,alpha'-dihydroxybiaryls with a single chiral stationary phase made from readily available amino acid derivatives. The stationary phase works well for biphenyl-type compounds. It works extremely well for larger bis-aromatic compounds, such as binaphthyl-type compounds.
[图：见正文] 使用由易于获得的氨基酸衍生物制成的单一手性固定相，对许多α,α'-二羟基联芳基化合物进行色谱分离时，观察到分离因子高达115。该固定相对联苯型化合物效果良好。对较大的双芳族化合物，如联萘型化合物，效果极佳。
