Almeida Maria Do Socorro Teixeira Moreira, Bértolo Manoel Barros, Da Silva Benedito Borges, De Deus Filho Antônio, Almeida Mayra Moreira, Veras Fabíola Ferreira Hortêncio, Mendes Luciano Cardoso
Internal Medicine Department, Federal University of Piauí, Rua Paissandu, 1772-Centro, Teresina-Piauí CEP 64001-120, Brazil.
Trop Doct. 2005 Oct;35(4):206-9. doi: 10.1258/004947505774938602.
To study the prevalence of connective tissue disorders and identify the epidemiological profile of the population from the northern and northeastern regions of Brazil. All patients admitted to the general medical ward at Getulio Vargas Hospital were screened through history and physical examination for the existence of known, suspected or possible connective tissue disorder. A total of 120 patients were enrolled in the study - 61 (50.8%) with systemic lupus erythematosus (SLE), 41 (34.2%) with rheumatoid arthritis (RA), 16 (13.3%) with systemic sclerosis (SS), one (0.8%) with mixed connective tissue disease (MCTD) and one (0.8%) with polymyositis (PM). Women accounted for (104) 86.7% of the participants and (83) 70.9% were non-Caucasians. The mean age was 36.8 years. Alopecia was the most frequent symptom (55/46.6%), followed by other cutaneous lesions (50/42.4%), dyspnea (47/39.8%) and chest pain (39/33.0%). The most frequent rheumatologic disorder encountered in our hospital-based study population was systemic lupus erythematosus, which is contrary to findings of the majority of studies performed in this country.
为研究结缔组织疾病的患病率，并确定巴西北部和东北部地区人群的流行病学特征。对入住热图利奥·瓦加斯医院普通内科病房的所有患者，通过病史和体格检查筛查是否存在已知、疑似或可能的结缔组织疾病。共有120名患者纳入研究——61例（50.8%）患有系统性红斑狼疮（SLE），41例（34.2%）患有类风湿关节炎（RA），16例（13.3%）患有系统性硬化症（SS），1例（0.8%）患有混合性结缔组织病（MCTD），1例（0.8%）患有多发性肌炎（PM）。女性占参与者的（104）86.7%，非白种人占（83）70.9%。平均年龄为36.8岁。脱发是最常见的症状（55/46.6%），其次是其他皮肤病变（50/42.4%）、呼吸困难（47/39.8%）和胸痛（39/33.0%）。在我们基于医院的研究人群中，最常见的风湿性疾病是系统性红斑狼疮，这与该国大多数研究的结果相反。
