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术前急性体重减轻对腹腔镜Roux-en-Y胃旁路手术的影响。

The effects of acute preoperative weight loss on laparoscopic Roux-en-Y gastric bypass.

作者信息

Liu Rockson C, Sabnis Adheesh A, Forsyth Celeste, Chand Bipan

机构信息

Department of General Surgery, Division of Minimally Invasive Surgery, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

出版信息

Obes Surg. 2005 Nov-Dec;15(10):1396-402. doi: 10.1381/096089205774859155.

DOI:10.1381/096089205774859155
PMID:16354518
Abstract

BACKGROUND

Minimal acute pre-operative weight loss significantly reduces liver size and intra-abdominal adipose tissue. We hypothesize that these changes will reduce intra-operative complications and reduce the difficulty of laparoscopic Roux-en-Y gastric bypass (LRYGBP).

METHODS

This is a retrospective chart review of consecutive patients who had undergone isolated LRYGBP between July 2003 and March 2005. All patients participated in our institution's medically supervised Weight Management Program before surgery.

RESULTS

48 patients (Weight Loss Group) had an average percent loss of excess weight (%EWL) of 4.6; whereas 47 patients (No Weight Loss Group) gained an average of 4.8% of excess weight over an average period of 2.4 and 3 months (P=0.09), respectively. There were no differences between the two groups in age, gender, ASA class, co-morbidities, or BMI at operation. The Weight Loss Group had less intra-operative blood loss (102 vs 72 ml, P=.03). The surgeon was also less likely to report an enlarged liver in the Weight Loss Group (P=.02). Finally, the operation was less likely to deviate from the standard LRYGBP when patients lost weight (P=.02). No differences were seen in operative time, length of hospital stay, wound infections, or major complications.

CONCLUSION

Acute preoperative weight loss is associated with less intra-operative blood loss and reduces the need for intraoperative deviation from the standard LRYGBP. A larger series with a greater reduction in excess weight is necessary to determine the maximal benefits of acute preoperative weight loss.

摘要

背景

术前少量的急性体重减轻可显著减小肝脏大小和腹内脂肪组织。我们推测这些变化将减少术中并发症,并降低腹腔镜Roux-en-Y胃旁路术(LRYGBP)的难度。

方法

这是一项对2003年7月至2005年3月期间连续接受单纯LRYGBP手术患者的回顾性病历审查。所有患者在手术前都参加了我们机构的医学监督下的体重管理计划。

结果

48例患者(体重减轻组)的超重平均减轻百分比(%EWL)为4.6;而47例患者(未减重组)在平均2.4个月和3个月的时间内分别平均超重增加了4.8%(P=0.09)。两组在年龄、性别、ASA分级、合并症或手术时的BMI方面无差异。体重减轻组术中失血量较少(102 vs 72 ml,P=0.03)。体重减轻组外科医生报告肝脏肿大的可能性也较小(P=0.02)。最后,当患者体重减轻时,手术偏离标准LRYGBP的可能性较小(P=0.02)。手术时间、住院时间、伤口感染或主要并发症方面未见差异。

结论

术前急性体重减轻与术中失血量减少相关,并减少了术中偏离标准LRYGBP的需要。需要进行更大样本量且超重减轻幅度更大的研究,以确定术前急性体重减轻的最大益处。

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