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[经颅磁刺激对视觉系统的检查]

[Examination of the visual system with transcranial magnetic stimulation].

作者信息

Meyer B U, Diehl R R

机构信息

Neurologische Klinik und Poliklinik, Technischen Universität, München.

出版信息

Nervenarzt. 1992 Jun;63(6):328-34.

PMID:1635614
Abstract

The influence of transcranially applied magnetic stimuli on the function of the afferent (sensory) and efferent (motor) parts of the visual system have been discussed. Excitatory (positive) phenomena are subjective photic sensations (phosphenes) which can be elicited by transcranial magnetic stimulation over occipital parts of the skull. The phosphenes appear on the left or right side of the visual field depending upon the direction of the coil currents, which determines whether the visual cortex of the right or the left hemisphere is activated. The configuration of the phosphene fields hints at an excitation of the primary visual cortex (Brodmann's area 17). However, magnetic brain stimulation also produces inhibitory (negative) phenomena. When strong magnetic field pulses are applied over the primary visual cortex, foveally presented visual stimuli cannot be identified even when no phosphenes are perceived at the same time. Depending on the position of the stimulation coil, this suppression of perception can be restricted to visual stimuli presented on the right, or left of, above or below the fixation point. No generation or disturbance of eye movements by transcranial magnetic stimulation has been reported before, except for a delay of saccades within a reaction time paradigm.

摘要

经颅施加磁刺激对视觉系统传入(感觉)和传出(运动)部分功能的影响已得到讨论。兴奋性(阳性)现象是主观光感(光幻视),可通过在颅骨枕部进行经颅磁刺激诱发。光幻视出现在视野的左侧或右侧,这取决于线圈电流的方向,而线圈电流方向决定了激活的是右半球还是左半球的视觉皮层。光幻视场的形态提示初级视觉皮层(布罗德曼17区)受到了刺激。然而,脑磁刺激也会产生抑制性(阴性)现象。当在初级视觉皮层施加强磁场脉冲时,即使同时未感觉到光幻视,也无法识别中央凹呈现的视觉刺激。根据刺激线圈的位置,这种感知抑制可局限于注视点右侧、左侧、上方或下方呈现的视觉刺激。除了在反应时范式中扫视延迟外,此前尚无经颅磁刺激导致眼球运动产生或受干扰的报道。

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