猫红核刺激诱发的Deiters神经元的逆向和突触激活。

Antidromic and synaptic activation of Deiters' neurons induced by stimulation of red nucleus in the cat.

作者信息

Sarkisian V H, Fanardjian V V

机构信息

Laboratory of Physiology of Central Nervous System, Orbeli Institute of Physiology, Academy of Sciences of Armenia, Yerevan.

出版信息

Neurosci Lett. 1992 Feb 17;136(1):47-50. doi: 10.1016/0304-3940(92)90644-m.

DOI:10.1016/0304-3940(92)90644-m

PMID:1635666

Abstract

Antidromic and orthodromic action potentials of neurons located in the lateral vestibular nucleus of Deiters' evoked by stimulation of red nucleus were studied in anaesthetized cats. Vestibulospinal neurons were identified by stimulation of the lateral vestibulospinal tract. The 'second-order' vestibular neurons were revealed by mean of stimulation of the ipsilateral VIIIth nerve. Stimulation of the red nucleus is shown to lead mainly to antidromic, as well as mono-, oligo- and polysynaptic activation of Deiters' neurons. Not any inhibitory reaction was observed in vestibular neurons in response to stimulation of the red nucleus. Ascending axon collaterals of the vestibulospinal neurons to this brainstem structure were revealed. The peculiarities and functional significance of the effects mentioned are discussed.

摘要

在麻醉猫中，研究了刺激红核诱发的位于Deiters外侧前庭核的神经元的逆向和顺向动作电位。通过刺激外侧前庭脊髓束来识别前庭脊髓神经元。通过刺激同侧第八对脑神经来揭示“二级”前庭神经元。结果表明，刺激红核主要导致Deiters神经元的逆向以及单突触、少突触和多突触激活。在前庭神经元中未观察到对刺激红核的任何抑制反应。揭示了前庭脊髓神经元向该脑干结构发出的上行轴突侧支。讨论了上述效应的特点和功能意义。