HIV疫苗设计：减毒活SIV疫苗的启示
HIV vaccine design: insights from live attenuated SIV vaccines.
作者信息
Koff Wayne C, Johnson Philip R, Watkins David I, Burton Dennis R, Lifson Jeffrey D, Hasenkrug Kim J, McDermott Adrian B, Schultz Alan, Zamb Timothy J, Boyle Rosanne, Desrosiers Ronald C
机构信息
International AIDS Vaccine Initiative, New York, New York 10038, USA.
出版信息
Nat Immunol. 2006 Jan;7(1):19-23. doi: 10.1038/ni1296.
DOI:10.1038/ni1296
PMID:16357854
Abstract
The International AIDS Vaccine Initiative has established a consortium to elucidate mechanisms of protection conferred by live attenuated simian immunodeficiency virus vaccines in monkeys. Here, the strategies defining key components of the protective immune response elicited by these vaccines are discussed.
摘要
国际艾滋病疫苗倡议组织已成立了一个联盟，以阐明减毒活猴免疫缺陷病毒疫苗在猴子体内产生保护作用的机制。在此，将讨论确定这些疫苗引发的保护性免疫反应关键组成部分的策略。
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