Ferreira Sandra R G, Almeida Bianca de, Siqueira Antonela F A, Khawali Cristina
Departamento de Medicina Preventiva, Universidade Federal de São Paulo, São Paulo, SP.
Arq Bras Endocrinol Metabol. 2005 Aug;49(4):479-83. doi: 10.1590/s0004-27302005000400003. Epub 2005 Oct 19.
Considering the increasing prevalence of diabetes mellitus (DM) in underdeveloped countries as well as the simplicity of identifying individuals at high risk for such disease, implementation of intervention measures for its prevention is of great interest. Several studies have confirmed the benefits of lifestyle changes in preventing or postponing the progression from impaired glucose tolerance to DM. The review of these studies showed a 50% to 60% reduction in the incidence of DM by means of lifestyle modifications. Such results are better than those reported in studies in which pharmacological interventions were used with the same purpose. Despite the efficacy of lifestyle changes for the prevention of DM, compliance may represent a limitation to be implemented in communities. In our country, studies are necessary to assess the barriers for the implementation of a population-based program for the prevention of DM and other lifestyle related diseases in high-risk Brazilian subjects.
考虑到糖尿病（DM）在不发达国家的患病率不断上升，以及识别此类疾病高危个体的简易性，实施预防干预措施备受关注。多项研究已证实生活方式改变在预防或延缓从糖耐量受损进展为糖尿病方面的益处。对这些研究的综述表明，通过生活方式改变，糖尿病发病率可降低50%至60%。这些结果优于那些使用相同目的的药物干预研究报告的结果。尽管生活方式改变对预防糖尿病有效，但依从性可能是在社区实施的一个限制因素。在我国，有必要开展研究，以评估在巴西高危人群中实施基于人群的糖尿病及其他生活方式相关疾病预防项目的障碍。
