Castagnola Elio, Molinari Angelo Claudio, Giacchino Mareva, Chiapello Nadia, Moroni Cristina, Caviglia Ilaria, Fratino Giuseppe, Haupt Riccardo
Department of Hematology and Oncology, Infectious Diseases Unit, G. Gaslini Children's Hospital, Genoa, Italy.
Pediatr Blood Cancer. 2007 Jan;48(1):35-8. doi: 10.1002/pbc.20724.
To evaluate the incidence of surgical site infections and bacteremias occurring within 30 days from insertion of partially implanted central venous catheters.
Four hundred eighteen devices positioned in children with cancer or undergoing bone marrow transplant were followed prospectively.
During a follow-up of 12,394 catheter-days, a total of 13 infectious episodes were documented, with an overall incidence of 3.1% and 1.05 episodes/1,000 catheter-days. Coagulase-negative staphylococci represented the causative pathogens of all episodes. Overall, surgical wound infections occurred in 1.4% of all catheters, with a rate of 0.48/1,000 catheter-days, while isolated bacteremias were observed in 1.7% of all inserted devices, with a rate of 0.57/1,000 catheter-days.
Infections are rare events within 30 days from insertion of partially implanted central venous catheters and coagulase-negative staphylococci represent the most frequently isolated cause of these complications.
评估部分植入式中心静脉导管插入后30天内手术部位感染和菌血症的发生率。
对418根植入癌症患儿或接受骨髓移植患儿体内的导管进行前瞻性随访。
在12394个导管日的随访期间,共记录到13次感染事件,总发生率为3.1%,每1000个导管日发生1.05次感染事件。凝固酶阴性葡萄球菌是所有感染事件的致病病原体。总体而言,手术伤口感染发生在所有导管的1.4%,发生率为每1000个导管日0.48次,而在所有插入装置的1.7%中观察到孤立性菌血症,发生率为每1000个导管日0.57次。
部分植入式中心静脉导管插入后30天内感染是罕见事件,凝固酶阴性葡萄球菌是这些并发症最常见的分离病因。