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[痴呆症中的血管因素]

[Vascular factors in dementia].

作者信息

Bidzan Leszek

机构信息

Klinika Psychiatrii Rozwojowej, Zaburzeń Psychotycznych i Wieku Podeszłego AM w Gdańsku.

出版信息

Psychiatr Pol. 2005 Sep-Oct;39(5):977-86.

Abstract

Cerebrovascular factors are a common cause of dementia or contribute to cognitive decline in other dementias. Studies showing that cerebrovascular factors are the risk factors for neurodegenerative dementias, especially Alzheimer's disease. Practically all neurodegenerative dementias have a vascular component that reduces cerebral perfusion and has great impact on the clinical picture. Recent data support the view that the neurodegenerative process is caused by cerebrovascular mechanisms. The results showed that patients with vascular cognitive impairment have a typical clinical picture. Various important non-cognitive features are caused by cerebrovascular factors and are associated with a more rapid course of illness. On the other hand the term vascular diseases or cerebrovascular factors include a variety of vascular pathologies.

摘要

脑血管因素是痴呆的常见病因,或促使其他类型痴呆出现认知功能减退。研究表明,脑血管因素是神经退行性痴呆的危险因素,尤其是阿尔茨海默病。实际上,所有神经退行性痴呆都有血管成分,会减少脑灌注,并对临床表现产生重大影响。最新数据支持神经退行性过程由脑血管机制引起这一观点。结果显示,血管性认知障碍患者具有典型的临床表现。各种重要的非认知特征由脑血管因素所致,并与病程进展更快相关。另一方面,血管疾病或脑血管因素这一术语包括多种血管病变。

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