Lee Jin-Yong, Eun Sang-Jun, Park Ki-Dong, Kim Jong-Kyun, Im Jeong-Soo, Hwang Yoo-Sung, Kim Yong-Ik
Department of Health Policy and Management, Seoul National University College of Medicine.
J Prev Med Public Health. 2005 Nov;38(4):449-56.
The biosafety level (BSL) practiced in microbiology laboratories in Korea according to the laboratory biosafety manual published by the World Health Organization (WHO) was evaluated using the data obtained by a survey.
Under the advise of Clinical Laboratory Physicians, 144 types of microorganisms were screened based on the guidelines of biosafety in microbiological and biomedical laboratories published by the US Center for Disease Control and Prevention and classified into 1-4 risk groups. A questionnaire containing 21 questions in 5 areas was developed using the biosafety manual by published WHO. Of the 1,876 different organizations sent the survey, 563 responded to the survey (response rate: 30.0%). The species of microoganisms handled by as well as the biosafety level in microbiology laboratories were analyzed.
There were 123 species of microorganisms handled in microbiology labs in Korea. The BSL required in 512 microbiology labs was answered by the survey responders as the first grade in 33 labs (6.4%), 2nd in 437 (85.4%), 3rd in 42 (8.2%), and 4th in none. The average number of items satisfied was 12.2, showing only a 57.9% satisfactory rate and normal distribution.
The state of overall observance of BSL in most microbiology labs of Korea was evaluated as lagging compared with the standard set up by WHO. Therefore, the Korean government need to produce and distribute a biosafety manual in microbiology laboratories and make efforts to prevent this threat through measures such as training in biosafety in microbiology labs.
利用一项调查获得的数据,对韩国微生物实验室依据世界卫生组织(WHO)发布的实验室生物安全手册所实行的生物安全水平(BSL)进行评估。
在临床实验室医师的建议下,根据美国疾病控制与预防中心发布的微生物学和生物医学实验室生物安全指南,筛选出144种微生物,并将其分为1 - 4个风险组。使用WHO发布的生物安全手册编制了一份包含5个领域21个问题的调查问卷。在发送调查的1876个不同组织中,563个组织回复了调查(回复率:30.0%)。对微生物实验室处理的微生物种类以及生物安全水平进行了分析。
韩国微生物实验室处理的微生物有123种。调查回复者对512个微生物实验室所需的生物安全水平回答为:一级的有33个实验室(6.4%),二级的有437个(85.4%),三级的有42个(8.2%),无四级的。平均满足项数为12.2项,满意度仅为57.9%,呈正态分布。
与WHO设定的标准相比,韩国大多数微生物实验室在生物安全水平总体遵守情况方面被评估为滞后。因此,韩国政府需要编制并分发微生物实验室生物安全手册,并通过微生物实验室生物安全培训等措施努力防范这种威胁。