Smits Jacqueline M A, Vanhaecke Johan, Haverich Axel, de Vries Erwin, Roels Leo, Persijn Guido, Laufer Gunther
Eurotransplant International Foundation, Leiden, The Netherlands.
Transpl Int. 2006 Jan;19(1):54-66. doi: 10.1111/j.1432-2277.2005.00234.x.
The prospects of patients on the thoracic waiting list are governed by the chance of receiving an organ in time and by the outcome of the transplantation. The former probability is determined by a triad of disease severity, resource size and allocation rules. The aim of this study was to provide an objective description of the distributional effects of the thoracic allocation system in Eurotransplant. It appears that the interpretation of waiting-list outflow indicators is not straightforward and that it is difficult to assess the fairness of an organ allocation system in the framework of changing donor-organ availability. The timing of listing for heart transplantation can substantially be improved; whether this is also true for lung transplantation cannot be determined from the available data. Allocation schemes cannot solve the problem of organ shortage; a shift of attention toward collaboration with procurement professionals is needed.
胸科等候名单上患者的前景取决于及时获得器官的机会以及移植的结果。前者的概率由疾病严重程度、资源规模和分配规则这三个因素决定。本研究的目的是对欧洲移植组织中胸科分配系统的分布效应进行客观描述。似乎等候名单流出指标的解读并非一目了然,而且在供体器官可用性不断变化的框架内评估器官分配系统的公平性很困难。心脏移植的登记时间可以大幅改善;从现有数据无法确定肺移植是否也是如此。分配方案无法解决器官短缺问题;需要将注意力转向与获取专业人员的合作。