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欧洲移植组织中的小儿心脏分配与移植

Pediatric heart allocation and transplantation in Eurotransplant.

作者信息

Smits Jacqueline M, Thul Josef, De Pauw Michel, Delmo Walter Eva, Strelniece Agita, Green Dave, de Vries Erwin, Rahmel Axel, Bauer Juergen, Laufer Guenther, Hetzer Roland, Reichenspurner Hermann, Meiser Bruno

机构信息

Eurotransplant International Foundation, Leiden, The Netherlands.

出版信息

Transpl Int. 2014 Sep;27(9):917-25. doi: 10.1111/tri.12356. Epub 2014 Jun 23.

DOI:10.1111/tri.12356
PMID:24853064
Abstract

Pediatric heart allocation in Eurotransplant (ET) has evolved over the past decades to better serve patients and improve utilization. Pediatric heart transplants (HT) account for 6% of the annual transplant volume in ET. Death rates on the pediatric heart transplant waiting list have decreased over the years, from 25% in 1997 to 18% in 2011. Within the first year after listing, 32% of all infants (<12 months), 20% of all children aged 1-10 years, and 15% of all children aged 11-15 years died without having received a heart transplant. Survival after transplantation improved over the years, and in almost a decade, the 1-year survival went from 83% to 89%, and the 3-year rates increased from 81% to 85%. Improved medical management of heart failure patients and the availability of mechanical support for children have significantly improved the prospects for children on the heart transplant waiting list.

摘要

在过去几十年里,欧洲移植组织(ET)的儿童心脏分配体系不断发展,以更好地服务患者并提高利用率。儿童心脏移植(HT)占ET年度移植总量的6%。多年来,儿童心脏移植等待名单上的死亡率有所下降,从1997年的25%降至2011年的18%。在列入名单后的第一年内,所有婴儿(<12个月)中有32%、所有1至10岁儿童中有20%以及所有11至15岁儿童中有15%在未接受心脏移植的情况下死亡。多年来,移植后的生存率有所提高,近十年来,1年生存率从83%提高到89%,3年生存率从81%提高到85%。心力衰竭患者医疗管理的改善以及儿童机械支持设备的可用性显著改善了心脏移植等待名单上儿童的前景。

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