Mikati Mohamad A, Shamseddine Alhan N
Department of Pediatrics, Adult and Pediatric Epilepsy Program, American University of Beirut Medical Center, Beirut, Lebanon.
Epilepsia. 2005;46 Suppl 10:48-50. doi: 10.1111/j.1528-1167.2005.00351.x.
We report a case with calculation-induced idiopathic generalized epilepsy (IGE) that, unlike most patients with IGE, was refractory to medications. This patient had a family history of (1) a similar condition in a relative of hers who, however, did not have identical manifestations, and (2) a mother who had migraine. Our observations illustrate that the occurrence of IGE in families usually follows rather complex patterns of inheritance and that some of them can be refractory to therapy.
我们报告了一例由计算诱发的特发性全身性癫痫（IGE）病例，与大多数IGE患者不同的是，该患者对药物治疗无效。该患者有家族病史：（1）她的一位亲属患有类似疾病，但表现并不完全相同；（2）她的母亲患有偏头痛。我们的观察结果表明，IGE在家族中的发生通常遵循相当复杂的遗传模式，其中一些对治疗可能无效。
