Porteous J W
Institute of Medical Sciences, School of Medical Science, University of Aberdeen, Aberdeen AB25 2ZD, Scotland, UK.
Cell Mol Biol (Noisy-le-grand). 2005 Dec 14;51(7):595-8.
All sciences progress by elaborating new concepts and by finding new relationships between the parts of a system of interacting components. Henrik Kacser, with a background in Biophysics and Genetics, was well placed to develop a new and comprehensive analysis of the control of metabolic fluxes and metabolite concentrations; and to demonstrate that changes in the concentration of normal metabolites were as important in Genetics as changes in the composition of metabolites in bringing about a change in trait.